Displaying drugs 9826 - 9850 of 14772 in total
T-900607
T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
Investigational
Matched Description: … T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer. …
PEG-uricase
PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment of severe, treatment-refractory gout in the United States in 2006.
Investigational
Matched Categories: … Enzymes and Coenzymes …
Forodesine
Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. Additional preliminary findings support its use for the management of some B-cell malignancies.
Investigational
Matched Description: … clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. ... rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
GC-373
GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription . GC-373 has been shown to inhibit the Mpro...
Experimental
Matched Description: … activates functional proteins involved in viral replication and transcription[A219036]. ... shown to inhibit the Mpro target in various coronavirus strains, including feline, mink, and ... inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Carotegrast methyl
Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and Efficacy of AJM300 in Participants With Active Ulcerative Colitis).
Investigational
Matched Description: … Carotegrast methyl is under investigation in clinical trial NCT03531892 (A Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Donanemab
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - pyroglutamate Aβ - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD). It works by inducing microglial-mediated clearance of existing Aβ...
Investigational
Matched Description: … A phase II study conducted by Eli Lilly and published in March 2021 (TRAILBLAZER-ALZ[L32724]), which …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Labetuzumab
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
NCX 1022
NCX is an NO-releasing derivative of hydrocortisone.
Investigational
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Zoalene
Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
Experimental
Vet approved
Matched Categories: … Benzamides and benzamide derivatives …
Luseogliflozin
Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Lintuzumab
Lintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
KRN-5500
KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pidilizumab
Pidilizumab is under investigation in clinical trial NCT01952769 (Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bizalimogene ralaplasmid
Bizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2).
Investigational
Matched Description: … VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Azvudine
Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).
Investigational
Matched Description: … Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
3-Amino-4-Oxybenzyl-2-Butanone
Experimental
Displaying drugs 9826 - 9850 of 14772 in total