Displaying drugs 9901 - 9925 of 14692 in total
INGN 201
INGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials. Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.
Investigational
Matched Description: … Advexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in ... combination with radiation and/or chemotherapy agents. ... replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and …
FP0011
FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). It acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.
Investigational
Matched Description: … FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects ... in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). ... It acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties. …
Acridine Carboxamide
Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
Investigational
Matched Description: … Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central …
SRT-2104
SRT2104 has been investigated for the basic science and treatment of Sepsis, PSORIASIS, Atrophy, Muscular, and Diabetes Mellitus, Type 2.
Investigational
Matched Description: … , and Diabetes Mellitus, Type 2. ... SRT2104 has been investigated for the basic science and treatment of Sepsis, PSORIASIS, Atrophy, Muscular …
Aticaprant
Aticaprant has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.
Investigational
Matched Description: … Disorders and Alcohol Dependence. ... Aticaprant has been used in trials studying the health services research and basic science of Anxiety …
AEE-788
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
Investigational
Matched Description: … AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and …
benzyl (2-oxopropyl)carbamate
Experimental
HOMOPHENYLALANINYLMETHANE
Experimental
Efonidipine
Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
Matched Description: … It has also been studied in atherosclerosis and acute renal failure [A32001]. ... This drug is also known as NZ-105, and several studies have been done on its pharmacokinetics in animals …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Categories: … Calcium-Regulating Hormones and Agents …
COVID19 s-vax loaded autologous dendritic cell vaccine
Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.
Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational
Matched Description: … presence of specific cytokines and growth factors. ... This vaccine was developed and tested by Beijing TIL Therapeutics. ... Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the …
Trevogrumab
Trevogrumab is under investigation in clinical trial NCT02943239 (Study of Safety, Tolerability, and Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women and Healthy Adult Men).
Investigational
Matched Description: … Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women and ... Trevogrumab is under investigation in clinical trial NCT02943239 (Study of Safety, Tolerability, and …
PF-04958242
PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing Loss, Sensorineural.
Investigational
Matched Description: … PF-04958242 has been used in trials studying the basic science and treatment of Schizophrenia and Hearing …
Perfosfamide
Perfosfamide has been used in trials studying the treatment of Lymphoma, Neuroblastoma, and Multiple Myeloma and Plasma Cell Neoplasm.
Investigational
Matched Description: … Myeloma and Plasma Cell Neoplasm. ... Perfosfamide has been used in trials studying the treatment of Lymphoma, Neuroblastoma, and Multiple …
NKG2D-ACE2 CAR-NK Cell
These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. Chimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling...
Investigational
Matched Description: … The transmembrane NKG2D and intracellular 2B4 domains are required for optimal NK signalling and subsequent ... transmembrane and signaling domains from T-cell receptor signalling moieties. ... cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and …
Adrafinil
Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. It is also been used off-label to prevent fatigue or falling asleep for extended periods of time. Adrafinil does not currently have FDA approval and is thus unregulated in the...
Withdrawn
Matched Description: … France's FDA equivalent reassessed the drug and withdrew marketing permission. ... Adrafinil does not currently have FDA approval and is thus unregulated in the United States. ... is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Azaperone
Azaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative and antiemetic effects. It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs and elephants. At the same time, the agent generally does not see equine use as particular adverse reactions may happen....
Investigational
Vet approved
Matched Description: … and antiemetic effects. ... It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs and elephants ... Azaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Barbital
A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug.
Illicit
Matched Description: … It is used as a hypnotic and sedative and may induce dependence. …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Aminoquinuride
Experimental
Coproporphyrinogen III
Experimental
OT-551
OT-551 is a novel small molecule that is topically dosed in an eye drop and has the unique ability to penetrate cell membranes and reach both the front and the back of the eye. It is intended to treat Age-related macular Degeneration (AMD), and preclinical research results indicate additional uses...
Investigational
Matched Description: … penetrate cell membranes and reach both the front and the back of the eye. ... OT-551 is a novel small molecule that is topically dosed in an eye drop and has the unique ability to ... additional uses for OT-551, including treatment of early stage and advanced dry age-related macular …
CX516
Investigational
Carbendazim
Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Description: … Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor …
Displaying drugs 9901 - 9925 of 14692 in total