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Displaying drugs 76 - 100 of 1932 in total
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … Idursulfase is produced by recombinant DNA technology in a human cell line. ... -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and mineral. Having critical roles in various applications inducing chemical and...
Approved
Investigational
Matched Description: … It has a high electrical conductivity, thermal conductivity, and reflectivity. ... 1800s, and they may be found in dental pastes as an active ingredients. ... Silver exists as a pure elemental form, alloy with other metals, and mineral. …
Matched Mixtures name: … G Sol …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … G SOL Sanitizing …
Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent. Panitumumab was granted FDA approval on 27 September 2006.
Approved
Investigational
Matched Description: … Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the ... human epidermal growth factor receptor (EGFR). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. It is a lipid conjugate pro-drug of the acyclic nucleotide analogue cidofovir[L34404,A235725] - this lipid conjugate improves drug delivery to the target cells and significantly reduces the nephrotoxicity typically associated with cidofovir therapy.[A235725,A235735] Due to its...
Approved
Investigational
Matched Description: … Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. ... which allows for a drug to be approved based on the results of well-controlled animal studies when human ... analogue [cidofovir][L34404,A235725] - this lipid conjugate improves drug delivery to the target cells and
Matched Categories: … Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... preparations for use in the treatment of inflammatory conditions and infections in the eye. …
Matched Mixtures name: … Welly Human Repair Kit ... THIOCILLINE 500 IU/G + 5 MG/G DERİ MERHEMİ, 30 G ... THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GR …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Ophthalmological and Otological Preparations ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … NEOFEED 490,000iu/g POWDER ... Neosun Soluble Powder 715mg/g ... Neomycin 528.5 mg/g Water Soluble Powder …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It is an FDA-approved food additive directly added to food products for human consumption. ... cosmetic, hair, and skincare products. ... and mineral oral tablets as an ingredient for protective coatings. …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Concentrate and Solvent for Solution for Infusion 60mg/1.5ml …
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Description: … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor ... anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors …
Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M . It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays. Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts...
Approved
Matched Description: … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B ... Bisoctrizole is not approved by the FDA, but is approved in the EU and other parts of the world as a ... UV-filter in sunscreens, day care products and skin lightening products at a maximum concentration of …
Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Investigational
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... It is produced through recombinant DNA technology in mammalian CHO cells. ... Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Description: … [A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately ... activates nuclear receptors to regulate epithelial cell growth and differentiation. ... [A257689] Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging …
Matched Mixtures name: … Acnatac 10 mg/g + 0,25 mg/g Gel ... CLİNDATRE 12 MG/G + 0,25 MG/G JEL, 30 GRAM ... Clindamycin Phosphate and Tretinion …
Matched Categories: … Cell Stimulants and Proliferants ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ESTERA 1 MG/G ... ESTERA 0,5 MG/G ... ESTERA 0,25 MG/G
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant ... DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of ... [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for …
Matched Categories: … Recombinant Proteins ... Immunoglobulin Fragments ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … Imazol duo 10 mg/g + 2,5 mg/g Creme ... MYKOFUNGIN 3 200MG+10MG/G ... MYKOFUNGIN 3 200MG+10MG/G
Matched Categories: … Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ANTIMYKAL 10 MG/G ... MYKOMED 10MG/G CREME ... Kerasal foot and toe …
Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like...
Approved
Matched Description: … Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and ... various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the Netherlands, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Approved
Vet approved
Matched Description: … , and urography. ... As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography …
Matched Mixtures name: … Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium ... Diatrizoate Meglumine and Diatrizoate Sodium …
Matched Products: … Hypaque Oral Powder 0.9974g/g
Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Description: … Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human ... patterns found in non-human cell lines led to decreased immunogenicity and longer half-life [A31525]. ... The harvested product is concentrated and purified by a series of chromatography steps. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and
Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this ... [L39130,L39135] Full safety and efficacy data on imdevimab are not yet available, and further evaluation ... authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and
Matched Mixtures name: … Casirivimab and Imdevimab ... Casirivimab and Imdevimab …
Matched Categories: … casirivimab and imdevimab ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize ... areas with disruption of the blood-brain barrier (BBB) and/or abnormal vascularity. ... DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and
Matched Products: … DOTAREM INJECTION 27.932 g/ 100 ml …
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and
Matched Mixtures name: … Dometuss-G ... G-Dologen ... LARITOL G
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … PANADOL TABLET 1 g ... MISALIV®SUPOSITORIOS 125 MG/2 G. ... ADOREM® BABY 3.2 G / 100 ML JARABE …
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … affinity to both α1- and α2-adrenoceptors. ... is used for regional anesthesia during dental procedures in children and adults. ... Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up nasal ... Up and up nasal ... Foster and Thrive Nasal …
Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody ... Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast …
Matched Categories: … HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and
Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Description: … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require ... In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and ... In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... vonoprazan, amoxicillin and metronidazole ... vonoprazan, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood …
Displaying drugs 76 - 100 of 1932 in total