Displaying drugs 976 - 1000 of 1040 in total
Chlorphenesin
Approved
Experimental
Matched Synonyms: … 3-(p-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
Matched Iupac: … 3-(4-chlorophenoxy)propane-1,2-diol …
2-Hydroxy-5-({1-[(4-Methylphenoxy)Methyl]-3-Oxoprop-1-Enyl}Amino)-L-Tyrosine
Experimental
Matched Name: … 2-Hydroxy-5-({1-[(4-Methylphenoxy)Methyl]-3-Oxoprop-1-Enyl}Amino)-L-Tyrosine …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched International brands: … Valdyne …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Isoliquiritigenin
Isoliquiritigenin is a precursor to several flavonones in many plants.
Experimental
Matched Synonyms: … (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propene-1-one …
N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine …
N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid …
LM-030
Investigational
Matched Synonyms: … L-ISOLEUCINE, N2-(2-METHYL-1-OXOPROPYL)-L-GLUTAMINYL-L-THREONYL-L-LEUCYL-(.ALPHA.S,3S,6R)-3-AMINO-6-HYDROXY …
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ... -5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate …
Matched Iupac: … 3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
Matched Iupac: … 3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
ABBV-CLS-7262
Investigational
Matched Synonyms: … fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate - 2-amino-2- (hydroxymethyl)propane …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Nerinetide
Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).
Investigational
Matched Synonyms: … -ASPARTYL-L-VALINE ... L-VALINE, L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE
Experimental
Matched Name: … N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE …
Rifampin
Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Synonyms: … piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate …
Matched Iupac: … -8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate …
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …
Matched Iupac: … -8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate …
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …
Prenylamine
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide
Experimental
Matched Name: … N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Synonyms: … Propane-1,2,3-triyl trinitrate …
Matched Description: … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
Matched Description: … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for ... [L6190]
Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects …
Matched Products: … VALKENE ... VALOIN INJECTION …
Matched Products: … VALKENE ... VALOIN INJECTION …
CT-179
Investigational
Matched Synonyms: … 1-(2-(3-(3,4-dichlorophenyl)ureido)-6-methyl-pyrimidin-4-yl)-amino-3(dimethylamino)propane …
Remifentanil
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives …
Matched Products: … SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE …
Matched Categories: … Fentanyl and fentanyl analogues ... Hypnotics and Sedatives …
Matched Products: … SERILONE® 2MG POLVO PARA SOLUCIÓN INYECTABLE …
Gandotinib
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … Adenosine triphosphate type 1 competitive inhibitor of JAK2 V617F tyrosine kinase …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and …
(3S)-3-(dioxidosulfanyl)-N-[(1Z)-3-oxoprop-1-en-1-yl]-4-(1H-1,2,3-triazol-1-yl)-D-valine
Experimental
Matched Name: … (3S)-3-(dioxidosulfanyl)-N-[(1Z)-3-oxoprop-1-en-1-yl]-4-(1H-1,2,3-triazol-1-yl)-D-valine …
Matched Iupac: … (1S)-1-carboxy-2-methyl-1-{[(1Z)-3-oxoprop-1-en-1-yl]amino}-3-(1H-1,2,3-triazol-1-yl)propane-2-sulfinate …
Matched Iupac: … (1S)-1-carboxy-2-methyl-1-{[(1Z)-3-oxoprop-1-en-1-yl]amino}-3-(1H-1,2,3-triazol-1-yl)propane-2-sulfinate …
Efocipegtrutide
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE …
N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE
Experimental
Matched Name: … N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE …
Efmarodocokin alfa
Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Investigational
Matched Synonyms: … HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN FC REGION (81-GLYCINE …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
Matched Description: … Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and …
{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
Experimental
Matched Name: … {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol
Experimental
Matched Name: … 2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol …
Matched Iupac: … 2-[(3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propyl)amino]-2-(hydroxymethyl)propane-1,3-diol …
Matched Iupac: … 2-[(3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propyl)amino]-2-(hydroxymethyl)propane-1,3-diol …
Displaying drugs 976 - 1000 of 1040 in total