Displaying drugs 9976 - 10000 of 11117 in total
Fimasartan
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Iupac: … 2-(2-butyl-4-methyl-6-oxo-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,6-dihydropyrimidin ... -5-yl)-N,N-dimethylethanethioamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cenicriviroc
Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
Investigational
Matched Iupac: … (5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl ... ]phenyl}-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide …
Matched Description: … HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GW-493838
GW493838 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Iupac: … (2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-{6-[(4-chloro-2-fluorophenyl)amino]-9H-purin-9- …
Fosifloxuridine nafalbenamide
Fosifloxuridine nafalbenamide is under investigation in clinical trial NCT03428958 (A Safety Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment).
Investigational
Matched Iupac: … benzyl (2S)-2-[({[(2R,3S,5R)-5-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan- ... 2-yl]methoxy}(naphthalen-1-yloxy)phosphoryl)amino]propanoate …
Vorolanib
Vorolanib is under investigation in clinical trial NCT03904719 (CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)).
Investigational
Matched Iupac: … N-[(3S)-1-(dimethylcarbamoyl)pyrrolidin-3-yl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene] ... methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
L-erythro-7,8-dihydrobiopterin
7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Experimental
Matched Iupac: … 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,7,8-tetrahydropteridin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
Experimental
Matched Name: … 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Imetelstat
Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Investigational
Matched Iupac: … -dihydropyrimidin-1-yl)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-amino-5-(6-amino-9H-purin-9-yl)oxolan-2-yl ... )amino]-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl 3-hexadecanamido-2- ... -1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(5-methyl-2,4-dioxo ... -1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(sulfanyl)phosphoryl)amino]-5-(2-amino-6-oxo-6,9 ... {[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-3-[({[(2S,3S,5R)-5-(4-amino-2-oxo-1,2 …
C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide
Experimental
Matched Name: … C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-[amino(hydroxy)methyl]-2-azido-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-[amino(hydroxy)methyl]-2-azido-6-(hydroxymethyl)oxane-3,4,5-triol …
PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID
Experimental
Matched Iupac: … (3R)-3-hydroxy-3-({2-[(2-hydroxyethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropyl 2,2-dimethylpropanoate …
Fluorescein lisicol
Fluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human, Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease.
Investigational
Matched Iupac: … 5-({[(5S)-5-carboxy-5-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo ... [8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanamido]pentyl]carbamothioyl}amino)-2-(3,6-dihydroxy-9H-xanthen …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Oleandrin
Oleandrin has been used in trials studying the treatment of Lung Cancer and Chemotherapeutic Agent Toxicity.
Experimental
Investigational
Matched Iupac: … (1S,2S,5S,7R,10R,11S,13S,14R,15R)-11-hydroxy-5-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl] ... oxy}-2,15-dimethyl-14-(5-oxo-2,5-dihydrofuran-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl …
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Description: … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified …
Pacanalotamab
Investigational
Bizelesin
Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … 1,3-bis({2-[(1S)-1-(chloromethyl)-5-hydroxy-8-methyl-1H,2H,3H,6H-pyrrolo[3,2-e]indole-3-carbonyl]-1H-indol ... -5-yl})urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Triciribine
Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.
Investigational
Matched Iupac: … (2R,3R,4S,5R)-2-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen ... -2-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
Pimodivir
Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Investigational
Matched Iupac: … (2S,3S)-3-[(5-fluoro-2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-4-yl)amino]bicyclo[2.2.2]octane ... -2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rogaratinib
Rogaratinib is under investigation in clinical trial NCT03762122 (Rogaratinib in Patients With Advanced Pretreated Squamous-cell Non-small Cell Lung Cancer (SQCLC)).
Investigational
Matched Iupac: … 4-{[4-amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin ... -7-yl]methyl}piperazin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Leptazoline B
Leptazoline B is a polar oxazoline from the Cyanobacterium Leptolyngbya sp. Also see Leptazoline A, Leptazoline C, and Leptazoline D.
Experimental
Matched Iupac: … (2S,3S)-3-[(4S,5S)-2-(5-chloro-2-hydroxyphenyl)-5-methyl-4,5-dihydro-1,3-oxazol-4-yl]-N-(1,3-dihydroxypropan ... -2-yl)-2,3-dihydroxypropanamide …
Vecabrutinib
Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers).
Investigational
Matched Iupac: … (3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-{[3-chloro-5-(trifluoromethyl)phenyl]amino}-2-oxo- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Isatoribine
Isatoribine is a selective agonist of TLR7.
Investigational
Matched Iupac: … 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H,3H,4H,7H-[1,3]thiazolo[4,5-d] …
Matched Salts cas: … 198832-38-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 198832-38-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Subasumstat
Subasumstat is under investigation in clinical trial NCT03648372 (A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Advanced or Metastatic Solid Tumors or Relapsed/refractory Hematologic Malignancies and in a Subset With Coronavirus Disease 2019 (COVID-19)).
Investigational
Matched Iupac: … [(1R,2S,4R)-4-[(5-{4-[(1R)-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl} ... pyrimidin-4-yl)amino]-2-hydroxycyclopentyl]methyl sulfamate …
D-naphthyl-1-acetamido boronic acid alanine
Experimental
Matched Name: … D-naphthyl-1-acetamido boronic acid alanine …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1S)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1S)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
L-naphthyl-1-acetamido boronic acid alanine
Experimental
Matched Name: … L-naphthyl-1-acetamido boronic acid alanine …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]dihydroxyboranuide …
2-(Thiomethylene)-4-Methylpentanoic Acid
Experimental
Matched Name: … 2-(Thiomethylene)-4-Methylpentanoic Acid …
Matched Iupac: … (2S)-4-methyl-2-(sulfanylmethyl)pentanoic acid …
Matched Iupac: … (2S)-4-methyl-2-(sulfanylmethyl)pentanoic acid …
Displaying drugs 9976 - 10000 of 11117 in total