Displaying drugs 10026 - 10050 of 14740 in total
N-(pyridin-3-ylmethyl)aniline
Experimental
Benzbromarone
Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
Investigational
Withdrawn
Matched Description: … , Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia. ... Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia …
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Description: … Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate …
Barbexaclone
Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. While barbexaclone has sedative properties, propylhexedrine has psychostimulant properties intended to offset these sedative effects. Pharmacokinetic studies have demonstrated that the pharmacokinetics of phenobarbital given as barbexaclone are not...
Experimental
Matched Description: … These reports were conducted in a small series of patients in the 1970s and 1980s, and have yet to be ... as phenobarbital in adults and children, while being better tolerated and having less sedative properties ... By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital. …
Matched Categories: … Barbiturates and Derivatives …
Matched Categories: … Barbiturates and Derivatives …
3,7-DIHYDROXYNAPHTHALENE-2-CARBOXYLIC ACID
Experimental
AMG-208
AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Investigational
Matched Description: … AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and …
Alizapride
Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects. This kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, including that which may occur postoperatively.
Investigational
Matched Description: … Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects ... of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Droloxifene
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene appears active and tolerable. ... Droloxifene may have an effect on bone and breast tissue because it induces apoptosis. ... Short-term toxicity was generally mild, and similar to that seen with other antiestrogens. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Dipipanone
Experimental
Illicit
Bis(N-maleimidomethyl)ether
Experimental
Trazeolide
Experimental
Covax-19™
Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. It uses an insect-cell-produced recombinant SARS-CoV-2 spike protein and Vaxine’s adjuvant, Advax-SM. This adjuvant is designed to circumvent high fevers, fatigue, and aches experienced with other vaccines using more traditional adjuvants. Covax-19™ was tested in animal studies, and...
Investigational
Matched Description: … Covax-19™ was tested in animal studies, and shown to achieve potent antibody and T-cell responses against ... Phase 2 and 3 trials are planned for September 2020, and the vaccine is expected to launch early in 2021 ... Covax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. …
BMS-813160
BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
Investigational
Matched Description: … and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC ... BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine …
Porphobilinogen
Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Experimental
Matched Description: … It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme …
6-o-Capryloylsucrose
Experimental
N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine
Experimental
(2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Sobetirome
Investigational
Indoleacetic acid
Experimental
Displaying drugs 10026 - 10050 of 14740 in total