Displaying drugs 1001 - 1025 of 1181 in total
MK-4541
MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Investigational
Matched Synonyms: … 9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate …
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Matched Description: … MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase ... MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). …
Colistin
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …
Anetumab ravtansine
Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-mesothelin antibody-drug conjugate BAY 94-9343 …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
CMG901
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
ABBV-CLS-7262
Investigational
Matched Synonyms: … Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Matched Iupac: … sodium 2-amino-2-(hydroxymethyl)propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido …
Satralizumab
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... central nervous system (CNS) involving demyelinating lesions in the optic nerve, spinal cord, brainstem, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... central nervous system (CNS) involving demyelinating lesions in the optic nerve, spinal cord, brainstem, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
SBT-100
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
AOC 1001
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting ... , effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA ( …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 ... (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Salts name: … Ganciclovir sodium …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and ... is driven by complement activation, which initiates a cascade that ultimately leads to both intra- and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in ... IgM) autoantibodies towards the I antigen on erythrocytes - these antibodies react optimally at 4°C and ... is driven by complement activation, which initiates a cascade that ultimately leads to both intra- and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Carboplatin
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of cisplatin with reduced nephrotoxicity and vomiting.[A230463,A230523]
Carboplatin was granted FDA approval on 3 March 1989.
Approved
Matched Description: … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents …
Matched Products: … CAREZ INJECTION 10 MG/ML ... CARMEN 50 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET ... CARMEN 150 MG/15 ML IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents …
Matched Products: … CAREZ INJECTION 10 MG/ML ... CARMEN 50 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET ... CARMEN 150 MG/15 ML IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ordesekimab
Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).
Investigational
Matched Synonyms: … Human IgG1 anti-IL-15 monoclonal antibody …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE
Experimental
Matched Name: … 1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE …
Matched Iupac: … 1-benzylcyclopentyl N-[(2S)-1-oxohexan-2-yl]carbamate …
Matched Iupac: … 1-benzylcyclopentyl N-[(2S)-1-oxohexan-2-yl]carbamate …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … PEGylated recombinant anti-Pseudomonas aeruginosa PcrV Fab' antibody ... KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS ... ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN, PEGYLATED HUMANIZED MONOCLONAL ANTIBODY …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... It is enriched in the liver, egg yolks, and the fat component of dairy products. …
Matched Mixtures name: … AVETAL-12 ... OQ-SEE ® ... OQ-SEE ® …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … OQ - SEE …
Matched Mixtures name: … AVETAL-12 ... OQ-SEE ® ... OQ-SEE ® …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … OQ - SEE …
Mirvetuximab soravtansine
Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound DM4 (also known as soravtansine or ravtansine).[A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1....
Approved
Investigational
Matched Synonyms: … Anti-FOLR1-monoclonal-antibody-maytansinoid-conjugate-IMGN-853 …
Matched Description: … DM4 leads to cell-cycle arrest and apoptosis and is also able to diffuse into neighboring cells and induce ... the surface of epithelial tumor cells, characteristic of ovarian, endometrial, triple-negative breast and ... [A254382] After an ADC/receptor complex is formed, mirvetuximab soravtansine-gynx is internalized, and …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Matched Description: … DM4 leads to cell-cycle arrest and apoptosis and is also able to diffuse into neighboring cells and induce ... the surface of epithelial tumor cells, characteristic of ovarian, endometrial, triple-negative breast and ... [A254382] After an ADC/receptor complex is formed, mirvetuximab soravtansine-gynx is internalized, and …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates …
Eluvixtamab
Investigational
Matched Synonyms: … A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AD-114
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Indigotindisulfonic acid
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and ... [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …
Matched Products: … SODIO INDIGOTINDISOLFONATO S.A.L.F. ... SODIO INDIGOTINDISULFONATO MONICO …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …
Matched Products: … SODIO INDIGOTINDISOLFONATO S.A.L.F. ... SODIO INDIGOTINDISULFONATO MONICO …
Displaying drugs 1001 - 1025 of 1181 in total