Displaying drugs 10226 - 10250 of 11105 in total
Sparteine
Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one...
Experimental
Withdrawn
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Iupac: … -3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide ... 4-{4-[bis(2-chloroethyl)amino]benzamido}-N-[5-({5-[(2-carbamimidoylethyl)carbamoyl]-1-methyl-1H-pyrrol …
Matched Salts cas: … 118438-45-2 …
Matched Salts cas: … 118438-45-2 …
Etonitazene
Experimental
Illicit
Matched Iupac: … (2-{2-[(4-ethoxyphenyl)methyl]-5-nitro-1H-1,3-benzodiazol-1-yl}ethyl)diethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Iodo-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-iodo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Fluoro-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Tetrahydrodeoxyuridine
Experimental
Matched Iupac: … 1-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
Nebularine
Experimental
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
HT-0712
BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Investigational
Matched Iupac: … (3S,5S)-5-[3-(cyclopentyloxy)-4-methoxyphenyl]-3-[(3-methylphenyl)methyl]piperidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Buparlisib
Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2,6-bis(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
GW842166
GW842166X has been used in trials studying the treatment of Pain, Analgesia, Inflammation, Osteoarthritis, and Pain, Inflammatory, among others.
Investigational
Matched Iupac: … 2-[(2,4-dichlorophenyl)amino]-N-[(oxan-4-yl)methyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rigosertib
Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Investigational
Matched Iupac: … 2-[(2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenyl)amino]acetic acid …
AZD-9056
AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … N-[(adamantan-1-yl)methyl]-2-chloro-5-{3-[(3-hydroxypropyl)amino]propyl}benzamide …
Oxametacin
Experimental
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxyacetamide …
Florasulam
Florasulam is under investigation in clinical trial NCT01193465 (Temperature and Humidity Among Different Anesthesia Work-station).
Investigational
Matched Iupac: … N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Acumapimod
Acumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Investigational
Matched Iupac: … 3-[5-amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ciclonium bromide
Experimental
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Miricorilant
Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and Recent Weight Gain While Taking Antipsychotic Medications (GRATITUDE)).
Investigational
Matched Iupac: … 6-[(1r,4r)-4-phenylcyclohexyl]-5-{[3-(trifluoromethyl)phenyl]methyl}-1,2,3,4-tetrahydropyrimidine-2,4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Vafidemstat
Vafidemstat is under investigation in clinical trial NCT03867253 (Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease).
Investigational
Matched Iupac: … 5-({[(1R,2S)-2-[4-(benzyloxy)phenyl]cyclopropyl]amino}methyl)-1,3,4-oxadiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BMS-833923
Investigational
Matched Iupac: … N-{2-methyl-5-[(methylamino)methyl]phenyl}-4-[(4-phenylquinazolin-2-yl)amino]benzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine
Experimental
Matched Name: … S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine …
Matched Iupac: … (2R)-2-amino-3-[(2-sulfamoylethyl)sulfanyl]propanoic acid …
Matched Iupac: … (2R)-2-amino-3-[(2-sulfamoylethyl)sulfanyl]propanoic acid …
O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
Experimental
Matched Name: … O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …
Matched Iupac: … 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …
N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
Experimental
Matched Name: … N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide …
Matched Iupac: … N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide …
Matched Iupac: … N-(4-chlorophenyl)-2-{[(pyridin-4-yl)methyl]amino}benzamide …
4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID
Experimental
Matched Name: … 4-(2-HYDROXY-4-FLUOROPHENYLTHIO)-BUTYLPHOSPHONIC ACID …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
Matched Iupac: … [(1E)-4-[(5-fluoro-2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION
Experimental
Matched Name: … 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION …
Matched Iupac: … 6-[2-(4-hydroxy-3-nitrophenyl)acetamido]hexanoate …
Matched Iupac: … 6-[2-(4-hydroxy-3-nitrophenyl)acetamido]hexanoate …
Buthionine sulfoximine
Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Synonyms: … Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)- …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid …
Displaying drugs 10226 - 10250 of 11105 in total