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Displaying drugs 10276 - 10300 of 12145 in total

N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE

Experimental

Potassium triiodide

Experimental

PAT-SM6

Investigational

5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione

Experimental

(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one

Experimental

LSP-GR3

Investigational

Sodium dichloroacetate

Investigational

Abequolixron

Investigational

Cilansetron

Cilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.
Investigational
Matched Iupac: … (12R)-12-[(2-methyl-1H-imidazol-1-yl)methyl]-1-azatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5(16), …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

R-82913

Experimental
Matched Iupac: … (11S)-6-chloro-11-methyl-10-(3-methylbut-2-en-1-yl)-1,3,10-triazatricyclo[6.4.1.0^{4,13}]trideca-4(13 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dexetimide

A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
Withdrawn
Matched Iupac: … (3S)-1'-benzyl-3-phenyl-[3,4'-bipiperidine]-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Romifidine

Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Gemigliptin

Gemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.
Investigational
Matched Iupac: … 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Siagoside

Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, …

2,3-Bis-Benzo[1,3]Dioxol-5-Ylmethyl-Succinic Acid

Experimental

Fasudil

Fasudil has been investigated in Carotid Stenosis.
Investigational
Matched Iupac: … 5-(1,4-diazepane-1-sulfonyl)isoquinoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dithiazanine

Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964. Dithiazanine iodide has been withdrawn from...
Vet approved
Withdrawn
Matched Iupac: … 3-ethyl-2-[5-(3-ethyl-2,3-dihydro-1,3-benzothiazol-2-ylidene)penta-1,3-dien-1-yl]-1,3-benzothiazol-3- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sagopilone

Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Iupac: … ,11S,12S,16R)-7,11-dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-1,3-benzothiazol-5-yl)-10-(prop-2-en-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Irsogladine

Irsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phenoperidine

Experimental
Matched Iupac: … ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cefozopran

Experimental
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}imidazo[1,2-b]pyridazin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetamido]-2-carboxy-8-oxo-5-thia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

GC-376 free acid

GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov...
Experimental
Matched Iupac: … -1-sulfonic acid ... (2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane …
Matched Description: … GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage ... A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro ... addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink M< …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Heme arginate

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sulfachlorpyridazine

A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
Vet approved
Matched Iupac: … 4-amino-N-(6-chloropyridazin-3-yl)benzene-1-sulfonamide …

Amineptine

The Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.
Illicit
Withdrawn
Matched Iupac: … 7-({tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}amino)heptanoic acid …
Displaying drugs 10276 - 10300 of 12145 in total