Displaying drugs 10326 - 10350 of 12047 in total
Rexin G
Rexin-G is a tumor-targeted, injectable retroviral vector carrying a mutant form of the cyclin G1 gene. It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.
Investigational
Guanosine
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal transduction pathways.
Experimental
Investigational
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Opiranserin
Opiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).
Investigational
Matched Iupac: … 4-butoxy-N-{[4-(dimethylamino)oxan-4-yl]methyl}-3,5-dimethoxybenzamide …
COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Tezacitabine
A synthetic purine nucleoside analogue with potential antineoplastic activity.
Investigational
Matched Iupac: … 4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin …
Matched Salts cas: … 171176-43-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 171176-43-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Adipiplon
Adipiplon is an nonbenzodiazepine anxiolytic developed by Neurogen Corporation. It is known by the standardized identifier NG2-73.
Investigational
Matched Iupac: … 3-fluoro-2-[1-({2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl}methyl)-1H-imidazol-2-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Surufatinib
Surufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).
Investigational
Matched Iupac: … N-[2-(dimethylamino)ethyl]-1-[3-({4-[(2-methyl-1H-indol-5-yl)oxy]pyrimidin-2-yl}amino)phenyl]methanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pyrazoloacridine
Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.
Investigational
Matched Iupac: … (3-{4-methoxy-10-nitro-8,14,15-triazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2,4,6,9(16),10,12 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Evogliptin
Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(tert-butoxy)methyl]piperazin-2-one …
Matched Categories: … Dipeptidyl Peptidase 4 ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … Dipeptidyl Peptidase 4 ... Heterocyclic Compounds, 1-Ring …
Fenoverine
Fenoverine has been used in trials studying the treatment of Irritable Bowel Syndrome.
Investigational
Matched Iupac: … 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-1-(10H-phenothiazin-10-yl)ethan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Captodiame
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Synonyms: … 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Salts cas: … 904-04-1 …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Salts cas: … 904-04-1 …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Glucoraphanin
Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]).
Investigational
Matched Synonyms: … 4-methylsulfinylbutyl glucosinolate …
Matched Iupac: … {[(E)-(5-methanesulfinyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}pentylidene …
Matched Iupac: … {[(E)-(5-methanesulfinyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}pentylidene …
Lintitript
Lintitript is a new, highly specific and potent CCK-A receptor antagonist.
Investigational
Matched Iupac: … 2-(2-{[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl}-1H-indol-1-yl)acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Salts cas: … 77-98-5 …
Matched Categories: … MATE 1 Substrates …
Matched Categories: … MATE 1 Substrates …
MK-212
MK-212 has been used in trials studying the treatment of Alcoholism.
Investigational
Matched Iupac: … 2-chloro-6-(piperazin-1-yl)pyrazine …
Matched Salts cas: … 61655-58-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 61655-58-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bentazepam
Experimental
Matched Iupac: … 14-phenyl-8-thia-10,13-diazatricyclo[7.5.0.0^{2,7}]tetradeca-1(9),2(7),13-trien-11-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
N-(Sulfanylacetyl)Tyrosylprolylmethioninamide
Experimental
Matched Iupac: … (2S)-2-{[(2S)-1-[(2S)-3-(4-hydroxyphenyl)-2-(2-sulfanylacetamido)propanoyl]pyrrolidin-2-yl]formamido} ... -4-(methylsulfanyl)butanamide …
Elamipretide
Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Investigational
Matched Iupac: … (2S)-6-amino-2-[(2S)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-3-(4-hydroxy-2,6-dimethylphenyl)propanamido ... ]-N-[(1S)-1-carbamoyl-2-phenylethyl]hexanamide …
SB719125
Investigational
4-[[(2S)-2-[[(2S)-3-Carboxy-2-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]butyl-(diaminomethylidene)azanium
Experimental
Matched Name: … 4-[[(2S)-2-[[(2S)-3-Carboxy-2-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]butyl-(diaminomethylidene …
Matched Iupac: … {4-[(2S)-2-[(2S)-3-carboxy-2-hydroxypropanamido]-4-methylpentanamido]butyl}(diaminomethylidene)azanium …
Matched Iupac: … {4-[(2S)-2-[(2S)-3-carboxy-2-hydroxypropanamido]-4-methylpentanamido]butyl}(diaminomethylidene)azanium …
2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide
Experimental
Matched Name: … 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino …
Matched Iupac: … 2-fluoro-6-[(2-{[4-(methanesulfonylmethyl)-2-methoxyphenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino …
Matched Iupac: … 2-fluoro-6-[(2-{[4-(methanesulfonylmethyl)-2-methoxyphenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino …
(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide
Experimental
Matched Name: … (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide …
Matched Iupac: … (2Z)-N-{[1,1'-biphenyl]-4-yl}-2-cyano-3-hydroxybut-2-enamide …
Matched Iupac: … (2Z)-N-{[1,1'-biphenyl]-4-yl}-2-cyano-3-hydroxybut-2-enamide …
2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide
Experimental
Matched Name: … 2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide …
Matched Iupac: … 2-(4-fluorobenzenesulfonamido)-N-oxoacetamide …
Matched Iupac: … 2-(4-fluorobenzenesulfonamido)-N-oxoacetamide …
4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide
Experimental
Matched Name: … 4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide …
Matched Iupac: … 4-[(6-chloropyrazin-2-yl)amino]benzene-1-sulfonamide …
Matched Iupac: … 4-[(6-chloropyrazin-2-yl)amino]benzene-1-sulfonamide …
Displaying drugs 10326 - 10350 of 12047 in total