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Displaying drugs 10351 - 10375 of 12253 in total
Experimental
Matched Iupac: … -5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinic acid ... {[hydroxy({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy})phosphoryl]oxy}({[(2R,3S,5R)-3-hydroxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Withdrawn
Matched Iupac: … 5-fluoro-N-hexyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 1-[(2E,4E,6E,8R)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl]pyrrolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease).
Investigational
Matched Iupac: … N-(5-{3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ciraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban).
Investigational
Matched Iupac: … (2S)-2-amino-N-[3-(4-{3-[(2S)-2-amino-5-carbamimidamidopentanamido]propyl}piperazin-1-yl)propyl]-5-carbamimidamidopentanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Denagliptin is under investigation in clinical trial NCT00387972 (Study of Denagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM)).
Investigational
Matched Iupac: … (2S,4S)-1-[(2S)-2-amino-3,3-bis(4-fluorophenyl)propanoyl]-4-fluoropyrrolidine-2-carbonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … D-leucyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … N-(2-OXOTETRAHYDROFURAN-3-YL)OCTANAMIDE …
Matched Iupac: … N-[(3S)-2-oxooxolan-3-yl]octanamide …
Experimental
Matched Name: … N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide …
Matched Iupac: … 2-(carboxymethoxy)-5-[(2S)-2-[(2S)-2-(3-carboxypropanamido)-3-phenylpropanamido]-2-(pentylcarbamoyl)ethyl …
A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Experimental
Matched Synonyms: … L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide …
Matched Iupac: … (4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo ... -1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid …
Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Synonyms: … Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)- …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid …
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Experimental
Matched Name: … N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE …
Matched Iupac: … N-[4-(phenylamino)quinazolin-6-yl]prop-2-enamide …
Experimental
Matched Synonyms: … Methyl 3-phenyl-L-alaninate …
Matched Iupac: … methyl (2S)-2-amino-3-phenylpropanoate …
Experimental
Matched Name: … [HYDROXY(3-PHENYLPROPYL)AMINO]METHANOL …
Matched Iupac: … [N-hydroxy-N-(3-phenylpropyl)amino]methanol …
Experimental
Matched Iupac: … (2S)-4-[(1-benzofuran-2-yl)methyl]-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(2R)-2-hydroxy-2,3-dihydro-1H-inden ... -1-yl]carbamoyl}butyl]-N-tert-butylpiperazine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Otamixaban is a novel direct Factor Xa (FXa) inhibitor. It is currently being developed by the French pharmaceutical company Sanofi-Aventis as a treatment for acute coronary syndrome.
Investigational
Matched Iupac: … 4-(4-{[(2R,3R)-3-[(3-carbamimidoylphenyl)methyl]-4-methoxy-4-oxobutan-2-yl]carbamoyl}phenyl)pyridin-1 ... -ium-1-olate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … {[(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene]amino}formonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.
Investigational
Matched Iupac: … 2-[N-(2,6-dimethylphenyl)-1-(1,1-dioxo-1lambda6-thian-4-yl)formamido]-N-[4-(1,2,4-oxadiazol-3-yl)phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.
Investigational
Matched Iupac: … 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Iupac: … 2-(5-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2-oxazol-5-yl}-2H-1,2,3,4-tetrazol-2-yl)acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Niaprazine is a selective brain catecholamine depletor.
Experimental
Matched Iupac: … N-{4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl}pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2R)-2-({4-[(6aS)-3-amino-1-oxo-1H,4H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic …
Displaying drugs 10351 - 10375 of 12253 in total