Niaprazine

DB13687InvestigationalSmall molecule

Niaprazine is a selective brain catecholamine depletor.

Mechanism: Pharmacologically active on Histamine H1 receptor, Alpha-1 adrenergic receptors, and 5-hydroxytryptamine 2 receptor
Curator reviewed
Formula / weight: C₂₀H₂₅FN₄O · 356.445 g/mol (avg)
Code names: 1709 CERM

Resolves to

Compound

Clinical / RWD

Structure

InChIKeyRSKQGBFMNPDPLR-UHFFFAOYSA-NSMILESCC(CCN1CCN(CC1)C1=CC=C(F)C=C1)NC(=O)C1=CN=CC=C1

Targets

What you can answer from here — as of July 07, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

668Drug interactionsStructured to mechanism, not free text

2Marketed productsAcross 1 country and 1 labeller

1ATC codeIncluding every combination product, plus 6 drug categories

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Niaprazine, and which of those have an active Phase 3 trial?

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