Displaying drugs 10351 - 10375 of 14740 in total
Octopamine
Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.
Experimental
Matched Description: … It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Amitraz
Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with...
Experimental
Vet approved
Matched Description: … Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. ... Amitraz is a non-systemic acaricide and insecticide. ... its driven inhibition of the synthesis of monoamine oxidases and prostaglandins. …
Queuine
Queuine is a derivative of 7-Deazaguanine. Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to plants and animals. Quantities of queuine have been found in tomatoes, wheat, coconut water, and milk from humans, cows, and goats. Humans salvage and recover queuine from either...
Experimental
Nutraceutical
Matched Description: … and goats. ... plants and animals. ... Humans salvage and recover queuine from either ingested food or the gut flora. …
Coblopasvir
Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).
Investigational
Matched Description: … Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir …
Lorundrostat
Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).
Investigational
Matched Description: … in Subjects With Uncontrolled and Resistant Hypertension). ... Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat …
Dinitrochlorobenzene
Dinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Categories: … Indicators and Reagents …
SNS-314
SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death. SNS-314 inhibits tumor growth in a variety of preclinical models, and...
Investigational
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single …
Picolinic acid
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Description: … It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities ... Picolinic acid has been shown to be an anti-viral in vitro and in vivo, and sometimes works in conjunction ... ZFPs are involved in viral replication and packaging as well as normal cell homeostatic functions. …
Betameprodine
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Vipadenant
Investigational
Furethidine
Experimental
Illicit
FM-VP4
FM-VP4, is a novel hydrophilic phytostanol analogue representing a new class in cholesterol-lowering drugs called cholesterol absorption inhibitors. FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total cholesterol in a broad range of animal species. Additional experiments suggest that FM-VP4 can reduce plasma LDL...
Investigational
Matched Description: … FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total ... levels, reduce weight gain and exert a anti-atherosclerosis effect. ... Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride …
Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)
The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells . This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West China Second University Hospital, and Yunan Center for Disease Control and Prevention. As...
Investigational
Matched Description: … Yunan Center for Disease Control and Prevention. ... SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and ... collaboration with the Chinese Academy of Medical Sciences, West China Second University Hospital, and …
Sodium copper chlorophyllin
Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties . This compound is used as a food colorant and supplement .
SCC of the commercial-grade is prepared from a reaction between a crude chlorophyll extract and methanolic...
Investigational
Matched Description: … that has potential antimutagenic and antioxidant properties[A227718]. ... This compound is used as a food colorant and supplement[A227718]. ... Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll …
AZD-8330
AZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.
Investigational
Matched Description: … active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and ... activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and …
Displaying drugs 10351 - 10375 of 14740 in total