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Displaying drugs 10376 - 10400 of 12247 in total

XomaZyme-791

Investigational

SC-236

SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
Experimental
Investigational
Matched Iupac: … 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PCI-27483

PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.
Investigational
Matched Iupac: … (2S)-2-{2-[5-(6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2',6-dihydroxy-5'-sulfamoyl-[1,1'-biphenyl]-3- …

Antithrombin gamma

Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational

Dinaciclib

Dinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
Investigational
Matched Iupac: … 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]pyridin ... -1-ium-1-olate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-2874455

LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Investigational
Matched Iupac: … 2-{4-[(E)-2-{5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl}ethenyl]-1H-pyrazol-1-yl}ethan ... -1-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Loperamide oxide

Experimental
Matched Iupac: … (1r,4s)-4-(4-chlorophenyl)-1-[3-(dimethylcarbamoyl)-3,3-diphenylpropyl]-4-hydroxypiperidin-1-ium-1-olate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Balovaptan

Balovaptan is under investigation in clinical trial NCT01793441 (A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)).
Investigational
Matched Iupac: … 12-chloro-8-methyl-3-[(1r,4r)-4-(pyridin-2-yloxy)cyclohexyl]-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca ... -1(14),3,5,10,12-pentaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Histamine glutarimide

Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma).
Investigational
Matched Iupac: … 1-[2-(1H-imidazol-5-yl)ethyl]piperidine-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Nitarsone

Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Vet approved
Matched Synonyms: … 4-nitrobenzenearsonic acid ... 4-nitrophenylarsonic acid …
Matched Iupac: … (4-nitrophenyl)arsonic acid …

N-Alpha-Acetyl-3,5-Diiodotyrosylglycine

Experimental
Matched Iupac: … 2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]acetic acid …

2'-fluoro-2'-deoxyuridine 3'-monophosphate

Experimental
Matched Name: … 2'-fluoro-2'-deoxyuridine 3'-monophosphate …
Matched Iupac: … {[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-yl] …

Bifidobacterium Longum Infantis 35624

Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]
Investigational

NGX267

NGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Investigational
Matched Iupac: … (2S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Amdoxovir

Investigational
Matched Iupac: … [(2R,4R)-4-(2,6-diamino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Metralindole

Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. In Russia, this drug was investigated for potential antidepressant activity.
Experimental
Matched Iupac: … 12-methoxy-4-methyl-1,4,6-triazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-5,9(16),10(15),11,13-pentaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …

Misonidazole

Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Investigational
Matched Iupac: … 1-methoxy-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Guadecitabine

Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Investigational
Matched Iupac: … {[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydro-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy}({[(2R ... ,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy})phosphinic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ingavirin

Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.
Investigational
Matched Iupac: … 4-{[2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tivantinib

Tivantinib has been investigated in Solid Tumors.
Investigational
Matched Iupac: … (3R,4R)-3-{1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4,6,8(12)-tetraen-3-yl}-4-(1H-indol-3-yl)pyrrolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bavisant

Bavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity.
Investigational
Matched Iupac: … 4-{[4-(4-cyclopropylpiperazine-1-carbonyl)phenyl]methyl}morpholine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Zipeprol

Experimental
Matched Iupac: … 1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Obidoxime

Experimental
Matched Iupac: … 4-[(E)-(hydroxyimino)methyl]-1-[({4-[(E)-(hydroxyimino)methyl]pyridin-1-ium-1-yl}methoxy)methyl]pyridin ... -1-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dotinurad

Dotinurad is under investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout).
Investigational
Matched Iupac: … 3-(3,5-dichloro-4-hydroxybenzoyl)-2,3-dihydro-1lambda6,3-benzothiazole-1,1-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bentiromide

Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is...
Investigational
Withdrawn
Matched Iupac: … 4-[(2S)-3-(4-hydroxyphenyl)-2-(phenylformamido)propanamido]benzoic acid …
Displaying drugs 10376 - 10400 of 12247 in total