Displaying drugs 10451 - 10475 of 12439 in total
Yttrium Y-90 clivatuzumab tetraxetan
Yttrium Y-90 clivatuzumab tetraxetan is under investigation in clinical trial NCT00603863 (Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer).
Investigational
Matched Description: … Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer). ... clivatuzumab tetraxetan is under investigation in clinical trial NCT00603863 (Safety and Efficacy Study of …
Gusacitinib
Gusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma).
Investigational
Matched Description: … of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma). ... Gusacitinib is under investigation in clinical trial NCT02550678 (A Study of the Efficacy and Safety …
ABX-PTH
ABX-PTH is a fully human monoclonal antibody generated by Abgenix's technology platform. This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary hyperparathyroidism.
Investigational
Matched Description: … This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary …
HMR4011
HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid. IPL 576,092 has previously been investigated as a treatment for asthma.
Investigational
Matched Description: … from that of glucocorticoid. ... HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct …
PF-06260414
PF-06260414 is under investigation in clinical trial NCT02070939 (Study To Evaluate Safety And Tolerability Of Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects).
Investigational
Matched Description: … Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects). ... 06260414 is under investigation in clinical trial NCT02070939 (Study To Evaluate Safety And Tolerability Of …
ABP-700
ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
Investigational
Matched Description: … is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of ... 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy). …
Sprifermin
Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee.
Investigational
Matched Description: … of Knee. ... Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury …
Bakuchiol
Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).
Investigational
Matched Description: … Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of …
Corticorelin
Corticotropin-releasing factor is studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone,...
Investigational
Matched Description: … It is a type of neurohormone, also called hCRF. ... Corticotropin-releasing factor is studied in the treatment of brain cancer. ... It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory …
Gevokizumab
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. ... Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's …
Pradefovir
Pradefovir is a prodrug of adefovir.
Investigational
Matched Description: … Pradefovir is a prodrug of [adefovir]. …
Veglin
VEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma. Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization in the ongoing struggle to combat malignant mesothelioma.
Investigational
Matched Description: … a variety of malignancies including mesothelioma. ... Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization ... non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of …
DDP733
DDP733 is an oral prokinetic drug which Dynogen is developing as a treatment for both Irritable Bowel Syndrome with constipation (IBS-c) and nocturnal gastroesophageal reflux disease (NGERD). It is a partial agonist of the serotonin type 3 receptor (5-HT3). Serotonin is a neurotransmitter that is known to be involved in...
Investigational
Matched Description: … the motility of the GI tract). ... It is a partial agonist of the serotonin type 3 receptor (5-HT3). ... Serotonin is a neurotransmitter that is known to be involved in the control of the gastrointestinal ( …
AEG35156
A second-generation synthetic antisense oligonucleotide with potential antineoplastic activity. AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP), a pivotal inhibitor of apoptosis that is overexpressed in many tumors. This agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs to overcome...
Investigational
Matched Description: … AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP) ... , a pivotal inhibitor of apoptosis that is overexpressed in many tumors. ... This agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs …
Zinc glycinate
Glycoprotein marker of gastrointestinal cancer.
Experimental
Matched Description: … Glycoprotein marker of gastrointestinal cancer. …
Aetiocholanolone
The 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]
Experimental
Matched Description: … The 5-beta-reduced isomer of androsterone. ... Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including …
Afelimomab
Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Investigational
Matched Description: … Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis. …
PF-06751979
PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Investigational
Matched Description: … Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults). ... -06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of …
Hemoximer
Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.
Investigational
Matched Description: … Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering …
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … mutase (MUT) gene into the genome of patients with methylmalonic acidemia. ... LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
ISP-001
ISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and delivery of alpha-L-iduronidase.
Investigational
Matched Description: … delivery of alpha-L-iduronidase. ... ISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and …
Prosetin
Prosetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic lateral sclerosis.
Investigational
Matched Description: … Prosetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic …
5-Methoxy-N,N-diisopropyltryptamine
5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects.
Experimental
Illicit
Matched Description: … Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. …
Custirsen
Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. Custirsen is also being investigated in...
Investigational
Matched Description: … of estrogen receptor-related mechanisms. ... Custirsen is also being investigated in the treatment of primary brain tumors. ... This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent …
SRP 299
SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting periodontal disease, in treating asthma and in treating eczema, itching and inflammation. Mycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity...
Investigational
Matched Description: … A specific subset of serotonergic neurons in the interfascicular part of the dorsal raphe nucleus (DRI ... SRP 299 is a preparation of killed Mycobacterium vaccae that has been tested in uses related to inhibiting ... saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of …
Displaying drugs 10451 - 10475 of 12439 in total