Displaying drugs 1026 - 1050 of 1390 in total
Cardiotrophin 1
Investigational
Matched Synonyms: … Protein cardiotrophin (human isoform 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
ALT-P1
ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Recombinant human growth hormone fused to alpha1-antitrypsin variant …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Matched Description: … ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. …
Exlinkibart
Investigational
Matched Synonyms: … factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus ... Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(p-Chlorophenyl)-gamma-aminobutyric acid ... gamma-Amino-beta-(p-chlorophenyl)butyric acid …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Categories: … Amino Acids, Peptides, and Proteins ... gamma-Aminobutyric Acid-ergic Agonist …
Matched Description: … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Categories: … Amino Acids, Peptides, and Proteins ... gamma-Aminobutyric Acid-ergic Agonist …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 19.79.5 .lambda. chain, dimer ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Libivirumab
Libivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Matched Synonyms: … with human monoclonal 17.1.41 .kappa. ... Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 17.1.41 heavy chain), disulfide …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Matched Description: … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD45 antigen) (mus musculus monoclonal BC8 gamma1-chain), disulfide with …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Respigam
Investigational
Matched Synonyms: … Respiratory syncytial virus immune globulin intravenous (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
CT-001
Investigational
Matched Synonyms: … Human recombinant factor VIIa variant (P10Q, K32E, T106N, V253N), desialylated …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide and Timolol …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … DORZOLAMID 1A PHARM20MG/ML ... Dorzolamid 1A Pharma 20 mg/ml – Augentropfen, Lösung …
Matched Mixtures name: … Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide and Timolol …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … DORZOLAMID 1A PHARM20MG/ML ... Dorzolamid 1A Pharma 20 mg/ml – Augentropfen, Lösung …
Azathioprine
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and ... A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … AZATHIOPRIN 1A PHARMA 25MG ... AZATHIOPRIN 1A PHARMA 50MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … AZATHIOPRIN 1A PHARMA 25MG ... AZATHIOPRIN 1A PHARMA 50MG …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide ... N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Angiotensin II
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Avalotcagene ontaparvovec
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 8 encoding human ornithine transcarbamylase ... Recombinant adeno-associated virus serotype AAV8 vector encoding human ornithine transcarbamylase …
Ciliary neurotrophic factor
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Matched Synonyms: … HUMAN CNTF ... HUMAN CILIARY NEUROTROPHIC FACTOR ... CILIARY NEUROTROPHIC FACTOR (HUMAN) …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular ... NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular ... NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Perenostobart
Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Investigational
Matched Synonyms: … Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human ... monoclonal SRF617 γ4-chain), disulfide with human monoclonal SRF617 κ-chain, dimer …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Synonyms: … 5-(gamma-methylaminopropyl)iminodibenzyl …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... as amitriptyline and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Modulators …
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... as amitriptyline and clomipramine. …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists ... Serotonin Agents ... Serotonin Modulators …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
Matched Description: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
Matched Description: … cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin …
3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine
Experimental
Matched Name: … 3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine …
Galantamine
Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Iupac: … (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15 …
Matched Description: … acetylcholine neurotransmission. ... and extended-release tablets and solution. ... [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and …
Matched Products: … Reminyl -(12mg) ... GALANTAMIN 1A PHAR16MG HAR ... GALANTAMIN 1A PHAR24MG HAR …
Matched Description: … acetylcholine neurotransmission. ... and extended-release tablets and solution. ... [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and …
Matched Products: … Reminyl -(12mg) ... GALANTAMIN 1A PHAR16MG HAR ... GALANTAMIN 1A PHAR24MG HAR …
Gatipotuzumab
Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).
Investigational
Matched Synonyms: … with human-mus musculus monoclonal pankomab-gex light chain, dimer ... Immunoglobulin g1, anti-(mucin muc1) (human-mus musculus monoclonal pankomab-gex heavy chain), disulfide …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … also has both anti-oxidant and anti-inflammatory properties. ... Pharmaceuticals and APOTEX have been available since the late 1990s. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and …
Matched Products: … PENTOXIFYLLIN 1A 400MG ... PENTOXIFYLLIN 1A 600MG …
Matched Products: … PENTOXIFYLLIN 1A 400MG ... PENTOXIFYLLIN 1A 600MG …
Displaying drugs 1026 - 1050 of 1390 in total