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Displaying drugs 10476 - 10500 of 13062 in total
Fenproporex
Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency....
Experimental
Illicit
Withdrawn
Matched Iupac: … 3-[(1-phenylpropan-2-yl)amino]propanenitrile …
Matched Description: … to yield amphetamine as a metabolite. [5] However, in clinical practice, central nervous system stimulative ... Structurally, fenproporex (N-2-cyanoethylamphetamine) falls within the phenylethamine and amphetamine ... The N-2-cyanoethyl substituent was once believed to be resistant to cleavage, because fenproporex -- …
Matched Description: … to yield amphetamine as a metabolite. [5] However, in clinical practice, central nervous system stimulative ... Structurally, fenproporex (N-2-cyanoethylamphetamine) falls within the phenylethamine and amphetamine ... The N-2-cyanoethyl substituent was once believed to be resistant to cleavage, because fenproporex -- …
2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol
Experimental
Matched Name: … 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
7-Aminodesacetoxycephalosporanic acid
Experimental
Matched Synonyms: … 3-methyl-7-aminoceph-3-em-4-carboxylic acid ... 7-amino-3-methyl-3-cephem-4-carboxylic acid ... 3-methyl-7-amino-Δ3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
N-(5'-Phosphopyridoxyl)-D-Alanine
Experimental
Matched Name: … N-(5'-Phosphopyridoxyl)-D-Alanine …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]propanoic acid …
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]propanoic acid …
CoA-S-acetyl 5-bromotryptamine
Experimental
Matched Name: … CoA-S-acetyl 5-bromotryptamine …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-{[2-({2-[({[2-(5-bromo-1H-indol-3-yl)ethyl]carbamoyl ... )(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... }methyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-{[2-({2-[({[2-(5-bromo-1H-indol-3-yl)ethyl]carbamoyl ... )(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... }methyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy …
5'-O-(L-Serylsulfamoyl)adenosine
Experimental
Matched Name: … 5'-O-(L-Serylsulfamoyl)adenosine …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) ... amino]-3-hydroxypropan-1-one …
Matched Iupac: … (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) ... amino]-3-hydroxypropan-1-one …
(C8-S)-Hydantocidin 5'-phosphate
Experimental
Matched Name: … (C8-S)-Hydantocidin 5'-phosphate …
Matched Iupac: … -3-yl]-2-[N-hydroxy-N-(hydroxymethyl)amino]pentanoic acid ... (2S)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …
Matched Iupac: … -3-yl]-2-[N-hydroxy-N-(hydroxymethyl)amino]pentanoic acid ... (2S)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these...
Investigational
Adenosine-5'-Propylphosphate
Experimental
Matched Name: … Adenosine-5'-Propylphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(propoxy)phosphinic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(propoxy)phosphinic acid …
6-aza uridine 5'-monophosphate
Experimental
Matched Synonyms: … 6-Azauridine-5'-monophosphate …
Matched Name: … 6-aza uridine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Name: … 6-aza uridine 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bicuculline
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
Experimental
Matched Iupac: … ^{2,6}]dodeca-1(9),2(6),7-trien-12-one ... (10R)-10-[(5S)-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3,5,11-trioxatricyclo[7.3.0.0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lifirafenib
Lifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Investigational
Matched Iupac: … 5-{[(2R,3R,4S)-3-[6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]-5-oxatricyclo[4.4.0.0^{2,4}]deca-1(6), ... 7,9-trien-9-yl]oxy}-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pidnarulex
Investigational
Matched Iupac: … 4-(4-methyl-1,4-diazepan-1-yl)-N-[(5-methylpyrazin-2-yl)methyl]-8-oxo-11-thia-1,3-diazatetracyclo[8.7.0.0 ... ^{2,7}.0^{12,17}]heptadeca-2(7),3,5,9,12,14,16-heptaene-9-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Bis(Adenosine)-5'-Triphosphate
Experimental
Matched Name: … Bis(Adenosine)-5'-Triphosphate …
Matched Iupac: … bis[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Iupac: … bis[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Deoxyuridine-5'-Triphosphate
Experimental
Matched Name: … Deoxyuridine-5'-Triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …
6-hydroxyuridine-5'-phosphate
Experimental
Matched Name: … 6-hydroxyuridine-5'-phosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy …
(6S)-5,6,7,8-tetrahydrofolic acid
Experimental
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic …
Adenosine 5'-methylenediphosphate
Experimental
Matched Synonyms: … Adenosine 5'-(hydrogen (phosphonomethyl)phosphonate) ... Adenosine, 5'-(trihydrogen methylenebis(phosphonate)) …
Matched Name: … Adenosine 5'-methylenediphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 5'-Nucleotidase, antagonists & inhibitors …
Matched Name: … Adenosine 5'-methylenediphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 5'-Nucleotidase, antagonists & inhibitors …
N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide
Experimental
Matched Name: … N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide …
Matched Iupac: … N-hydroxy-2-[N-(2-hydroxyethyl)[1,1'-biphenyl]-4-sulfonamido]acetamide …
Matched Iupac: … N-hydroxy-2-[N-(2-hydroxyethyl)[1,1'-biphenyl]-4-sulfonamido]acetamide …
4-Hydroxyphenylglycine
Experimental
Matched Synonyms: … (RS)-2-(4-hydroxyphenyl)glycine …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Oxfenicine
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … L-2-(p-hydroxyphenyl)glycine …
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid …
Fianlimab
Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma).
Investigational
Matched Synonyms: … Anti-lag-3 monoclonal antibody regn3767 …
Matched Description: … Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 …
Matched Description: … Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 …
Pipendoxifene
ER modulator, ERA-923(Pipendoxifene) is a estrogen receptor modulator being evaluated for the treatment of breast cancer. Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an excellent preclinical pharmacological profile and was selected for further development as a treatment for metastatic breast cancer.
Investigational
Matched Iupac: … 2-(4-hydroxyphenyl)-3-methyl-1-({4-[2-(piperidin-1-yl)ethoxy]phenyl}methyl)-1H-indol-5-ol …
Matched Description: … Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID
Experimental
Matched Name: … 2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid …
Thallium Tl-201
Thallium Tl-201 is under investigation in clinical trial NCT02697760 (The CZT Dynamic Myocardial Perfusion Imaging).
Investigational
Displaying drugs 10476 - 10500 of 13062 in total