Displaying drugs 10576 - 10600 of 12564 in total
Pentaglobin
Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) (https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).
Investigational
Matched Description: … Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin ... [A220173] It is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin …
SB 11285
SB 11285 is a second-generation Stimulator of Interferon Genes (STING) agonist. SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors).
Investigational
Matched Description: … SB 11285 is a second-generation Stimulator of Interferon Genes (STING) agonist. ... L45123] SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human ... It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known …
SIG-007
SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A. Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.
Investigational
Matched Description: … Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease. ... SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Description: … It is being investigated for the treatment of X-linked chronic granulomatous disease. ... OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
ETC-588
ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol and other lipids from cells including those in the arterial wall. LUV are capable of transporting excess cholesterol from the vasculature to...
Investigational
Matched Description: … of atherosclerosis. ... as part of the reverse lipid transport (RLT) pathway. ... ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through …
Deoxyribonuclease I
Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum,...
Investigational
Matched Description: … Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for ... airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory ... Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723 …
NM-702
Nissan Chemical and Taisho have been jointly developing NM-702, a drug for the treatment of arteriosclerosis obliterans.
M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. In Japan, Phase 2 studies are being conducted for intermittent claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis,...
Investigational
Matched Description: … sclerosis of peripheral arteries. ... Intermittent claudication is a major symptom of arteriosclerosis obliterans. ... M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. …
Sprifermin
Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee.
Investigational
Matched Description: … of Knee. ... Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury …
Bakuchiol
Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of Bakuchiol and Retinol).
Investigational
Matched Description: … Bakuchiol is under investigation in clinical trial NCT03112863 (Comparison of the Cosmetic Effects of …
Imolamine
Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine. It is developed under the brand name Coremax by Novartis consumer health SA.
Investigational
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3 …
Motexafin lutetium
Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Investigational
Matched Description: … It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. ... Motexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer …
Ripertamab
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Description: … Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of ... cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of …
Velsecorat
Velsecorat is under investigation in clinical trial NCT02479412 (A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma).
Investigational
Matched Description: … Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma ... investigation in clinical trial NCT02479412 (A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of …
Sarconeos
Sarconeos is an activator of the MAS receptor.
Investigational
Matched Description: … Sarconeos is an activator of the MAS receptor. …
Inactivated SARS-Cov-2 Vaccine
Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. This strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. Double-blind, randomized, placebo-controlled phase 1 (96 participants) and phase 2 (224...
Investigational
Matched Description: … strain of SARS-CoV-2. ... Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 ... [A220158] Results from these trials showed low rates of adverse reactions and demonstrated immunogenicity …
Ginsenoside Rb1
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex...
Nutraceutical
Matched Description: … claims of ginseng's efficacy. ... Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant ... Ginsenosides have been the target of research, as they are viewed as the active compounds behind the …
ISP-001
ISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and delivery of alpha-L-iduronidase.
Investigational
Matched Description: … delivery of alpha-L-iduronidase. ... ISP-001 consists of sleeping beauty transposon-engineered autologous plasmablasts for expression and …
Prosetin
Prosetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic lateral sclerosis.
Investigational
Matched Description: … Prosetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic …
IMA901
IMA901 is a vaccine consists of tumor-associated peptides (TUMAPs).
Investigational
Matched Description: … IMA901 is a vaccine consists of tumor-associated peptides (TUMAPs). …
Napabucasin
Napabucasin has been investigated for the treatment of Colorectal Carcinoma.
Investigational
Matched Description: … Napabucasin has been investigated for the treatment of Colorectal Carcinoma. …
Cerlapirdine
Cerlapirdine has been investigated for the treatment of Alzheimer Disease.
Investigational
Matched Description: … Cerlapirdine has been investigated for the treatment of Alzheimer Disease. …
Puerarin
Puerarin has been investigated for the treatment of Alcohol Abuse.
Investigational
Matched Description: … Puerarin has been investigated for the treatment of Alcohol Abuse. …
AC-430
AC430 has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Description: … AC430 has been investigated for the treatment of Rheumatoid Arthritis. …
Vamifeport
Vamifeport is being investigated for the treatment of beta-thalassemia.
Investigational
Matched Description: … Vamifeport is being investigated for the treatment of beta-thalassemia. …
Displaying drugs 10576 - 10600 of 12564 in total