Displaying drugs 1051 - 1075 of 1129 in total
Arcitumomab
Investigational
Matched Synonyms: … -chain anti-human antigen cea), disulfide with mouse monoclonal immu-4 light chain ... -chain anti-human antigen cea), disulphide with mouse monoclonal immu-4 light chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cosfroviximab
Investigational
Matched Synonyms: … musculus monoclonal c13c6-fr1 heavy chain), disulfide with human-mus musculus monoclonal c13c6-fr1 . ... Immunoglobulin g1, anti-(ebolavirus/reston ebolavirus/sudan ebolavirus/tai forest ebolavirus glycoprotein) (human-mus …
VaxSyn
VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the National Institute of Allergy and Infectious Diseases (NIAID).
Investigational
Matched Synonyms: … Human T-lymphotropic virus type III Gp160 antigens …
Matched Description: … National Institute of Allergy and Infectious Diseases (NIAID). ... VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the …
Matched Description: … National Institute of Allergy and Infectious Diseases (NIAID). ... VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the …
Lintuzumab satetraxetan AC-225
Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational
Matched Synonyms: … HUM-195 AC-225 ... Actinium-225-labeled humanized anti-cd33 monoclonal antibody HUM195 …
Matched Description: … trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody …
Matched Description: … trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Monoclonal antibody SGN-30 …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
Matched Description: … antibody with the drug monomethyl auristatin E (MMAE). ... It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antibody-drug Conjugates ... CD30-directed Antibody Interactions …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
AAV2/8.TBG.hARSB
Investigational
Matched Synonyms: … serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of the human …
AVE9633
AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate.
Investigational
Matched Synonyms: … huMy9-6-DM4 …
Matched Description: … AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … AVE9633 is an anti-CD33 monoclonal antibody-DM4 conjugate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Various Alimentary Tract and Metabolism Products ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Various Alimentary Tract and Metabolism Products ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AVR-RD-04
AVR-RD-04 is an investigational gene therapy for cystinosis. It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.
Investigational
Matched Synonyms: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
Matched Description: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
Matched Description: … transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human …
Pyridostigmine
Myasthenia gravis is an autoimmune disease involving dysfunction at the neuromuscular junction, most commonly due to autoantibodies directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and fatigue. Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the...
Approved
Investigational
Matched International brands: … Antilon …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Matched Description: … under various brand and generic names. ... directed against the acetylcholine receptor (AChR), which results in muscle tone loss, muscle weakness, and ... By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and …
Iluzanebart
Investigational
Matched Synonyms: … on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain ... Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed …
Belzupacap Sarotalocan
Investigational
Matched Synonyms: … Human papillomavirus virus-like particles conjugated with ir700 dye au-011 …
L-3972-T
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Bone morphogenetic protein 2 (human recombinant rhBMP-2) …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and ... at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and ... at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
Matched Synonyms: … genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Matched Description: … genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists …
Olenasufligene relduparvovec
Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Matched Description: … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene. …
Glenzocimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ibandronate
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol …
Matched Products: … IPEXAL …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... ibandronic acid and colecalciferol …
Matched Products: … IPEXAL …
Clervonafusp alfa
Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December ... It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … works by inhibiting the inflammatory signaling pathway of IL-36,[L43090] which is often overexpressed and ... Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December ... It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
RP-A501
RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …
St. John's Wort
Approved
Investigational
Nutraceutical
Matched Synonyms: … Hypoxis hemerocallidea root extract …
Matched Categories: … Herbs and Natural Products …
Matched Categories: … Herbs and Natural Products …
Displaying drugs 1051 - 1075 of 1129 in total