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Displaying drugs 10726 - 10750 of 12994 in total
Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.[A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB) with a fast onset of action and the ability to control gastric pH for a prolonged period of time.[A234215,...
Investigational
Matched Iupac: … 7-{[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy}-N,N,2-trimethyl-1H-1,3-benzodiazole-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
Matched Iupac: … (1R,2R,3R,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden …
An androgen receptor modulator.
Experimental
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Investigational
Matched Iupac: … N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-[4-(pyridin-2-yl)phenyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Filibuvir has been used in trials studying the treatment of Hepatitis, Hepatitis C, and Chronic Hepatitis C.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … N-benzyl-N-[2-(pyrrolidin-1-yl)ethyl]aniline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fulacimstat is under investigation in clinical trial NCT02452515 (A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction).
Investigational
Matched Iupac: … 1H-inden-1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ... 1-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 5-[(morpholin-4-yl)methyl]-3-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]-1,3-oxazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cyclotheonamide A is a cyclic peptide isolated from the marine sponge Theonella.
Experimental
Experimental
Matched Name: … 4-Imino-5-methidyl-2-trifluoromethylpyrimidine …
Matched Iupac: … 5-methylidene-2-(trifluoromethyl)-4,5-dihydropyrimidin-4-imine …
Experimental
Matched Iupac: … 2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}(methyl)amino)ethan-1-ol …
Metharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Withdrawn
Matched Iupac: … 5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Porfiromycin is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anticancer antibiotics.
Investigational
Matched Iupac: … ,8S)-11-amino-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca-1( …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
Investigational
Matched Iupac: … 1-{1-[(2S)-3-[(6-chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl]piperidin-4-yl}-1,3-diazinan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Investigational
Matched Iupac: … 6-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Englitazone is a hypoglycemic agent.
Experimental
Matched Iupac: … 5-{[(2R)-2-benzyl-3,4-dihydro-2H-1-benzopyran-6-yl]methyl}-1,3-thiazolidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10726 - 10750 of 12994 in total