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Displaying drugs 10751 - 10775 of 12512 in total

Mebhydrolin

Experimental
Matched Iupac: … 5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Xanomeline

Xanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium).
Investigational
Matched Iupac: … 5-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fialuridine

Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
Investigational
Matched Iupac: … 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phenothiazine

Phenothiazine (PTZ) is an organic thiazine compound.
Experimental
Vet approved

O1-Methyl-4-Deoxy-4-Thio-Alpha-D-Glucose

Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-2-methoxy-5-sulfanyloxane-3,4-diol …

Idazoxan

Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
Investigational
Matched Iupac: … 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …

Hemoporfin

Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Investigational
Matched Iupac: … 3-[20-(2-carboxyethyl)-10,15-bis(1-hydroxyethyl)-5,9,14,19-tetramethyl-21,22,23,24-tetraazapentacyclo ... [16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-4-yl]propanoic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-07304814

PF-07304814 is a small molecule prodrug that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 to assemble and multiply . Once administered through intravenous infusion, the compound is cleaved into PF-00835231 to exert its anti-viral effects . PF-07304814, developed by Pfizer, was first identified during the...
Investigational
Matched Iupac: … [(3S)-3-[(2S)-2-[(4-methoxy-1H-indol-2-yl)formamido]-4-methylpentanamido]-2-oxo-4-[(3S)-2-oxopyrrolidin …
Matched Description: … that targets the 3CLpro protease (Mpro), which is used by viruses like SARS-CoV-2 ... Now, it is being tested regarding the novel SARS-CoV-2 virus, including studies in conjunction with [ …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

N-(Sulfanylacetyl)Tyrosylprolylmethioninamide

Experimental
Matched Iupac: … (2S)-2-{[(2S)-1-[(2S)-3-(4-hydroxyphenyl)-2-(2-sulfanylacetamido)propanoyl]pyrrolidin-2-yl]formamido} …

Elamipretide

Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Investigational
Matched Iupac: … ]-N-[(1S)-1-carbamoyl-2-phenylethyl]hexanamide ... (2S)-6-amino-2-[(2S)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-3-(4-hydroxy-2,6-dimethylphenyl)propanamido …

N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID

Experimental
Matched Name: … N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID …
Matched Iupac: … 5-[methyl({4-[(1E)-2-(4-nitrophenyl)ethenyl]phenyl})amino]pentanoic acid …

Fresolimumab

Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.
Investigational

Golnerminogene pradenovec

Investigational

N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate

Experimental
Matched Name: … N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid …

Tifuvirtide

Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational

COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection

As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational

Novolimus

Novolimus is under investigation in clinical trial NCT04483791 (Dynamx Bioadaptor Hong Kong Registry).
Investigational

Guanosine-2',3'-cyclophosphorothioate

Experimental
Matched Name: … Guanosine-2',3'-cyclophosphorothioate …
Matched Iupac: … 9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-sulfanylidene-tetrahydro-2H-2lambda5-furo[3,4-d][ ... 1,3,2]dioxaphosphol-4-yl]-2-amino-6,9-dihydro-3H-purin-6-one …

(4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID

Experimental
Matched Name: … (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID …
Matched Iupac: … (2R,4S)-2-amino-4-[(naphthalen-2-yl)methyl]pentanedioic acid …

2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID

Experimental
Matched Name: … 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID …
Matched Iupac: … 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid …

Paclitaxel trevatide

Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.
Investigational
Matched Synonyms: … [a-N-(2'succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2'succinyl-paclitaxel)Lys ... ]-Arg-Asn-Asn-Phe-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr …
Matched Description: … paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, …

Batimastat

Experimental
Matched Iupac: … (2R,3S)-N'-hydroxy-N-[(1S)-1-(methylcarbamoyl)-2-phenylethyl]-2-(2-methylpropyl)-3-[(thiophen-2-ylsulfanyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Verdoheme

Experimental
Matched Iupac: … 19-(2-carboxyethyl)-4,9-diethenyl-5,10,14,20-tetramethyl-7-oxa-2,22lambda5,23,25-tetraaza-1-ferraoctacyclo ... [11.9.1.1^{1,8}.1^{3,21}.0^{2,6}.0^{16,23}.0^{18,22}.0^{11,25}]pentacosa-3,5,8,10,12,14,16,18(22),19,21 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Saredutant

Saredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.
Investigational
Matched Iupac: … N-[(2S)-2-(3,4-dichlorophenyl)-4-(4-acetamido-4-phenylpiperidin-1-yl)butyl]-N-methylbenzamide …
Matched Description: … Saredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Receptors, Neurokinin-2, antagonists & inhibitors …

Verinurad

Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.
Investigational
Matched Iupac: … 2-{[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]sulfanyl}-2-methylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10751 - 10775 of 12512 in total