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Displaying drugs 10776 - 10800 of 13227 in total

Golexanolone

Investigational
Matched Iupac: … (1E,3aS,3bR,5aS,7S,9aS,9bS,11aS)-7-ethynyl-1-(hydroxyimino)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …

4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION

Experimental
Matched Name: … 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION …
Matched Iupac: … 6-[2-(4-hydroxy-3-nitrophenyl)acetamido]hexanoate …

2,3,4,5,6-Pentafluorobenzyl Alcohol

Experimental

2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL

Experimental
Matched Name: … 2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL …
Matched Iupac: … (2R)-2-[(1R,2S)-2-hydroxycyclopentyl]pent-4-enal …

Halofuginone

Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Acetyleneurea

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Asimadoline

Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of...
Investigational
Matched Iupac: … N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methyl-2,2-diphenylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-03758309

PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Investigational
Matched Iupac: … N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-({2-methylthieno[3,2-d]pyrimidin-4-yl}amino)- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-04418948

Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers).
Investigational
Matched Iupac: … 1-(4-fluorobenzoyl)-3-{[(6-methoxynaphthalen-2-yl)oxy]methyl}azetidine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Radiprodil

Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.
Investigational
Matched Iupac: … 2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-5190457

PF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).
Investigational
Matched Iupac: … 2-{2-methylimidazo[2,1-b][1,3]thiazol-6-yl}-1-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden ... -1-yl]-2,7-diazaspiro[3.5]nonan-7-yl}ethan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-06700841

PF-06700841 is under investigation in clinical trial NCT03236493 (Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy Volunteers).
Investigational
Matched Iupac: … 4-[(1R,5S)-8-[(1S)-2,2-difluorocyclopropanecarbonyl]-3,8-diazabicyclo[3.2.1]octan-3-yl]-N-(1-methyl-1H-pyrazol ... -4-yl)pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lapaquistat

Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Investigational
Matched Iupac: … -4,1-benzoxazepin-3-yl]acetyl}piperidin-4-yl)acetic acid ... 2-(1-{2-[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide

Experimental
Matched Name: … 6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoyl-4-[(pyrimidin-2-yl)amino]naphthalene-2-carboxamide …

4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE

Experimental
Matched Name: … 4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE …
Matched Iupac: … 4-[({7-oxo-7H-[1,3]thiazolo[5,4-e]indol-8-yl}methyl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide …

Chromophore (Met-Tyr-Gly)

Experimental
Matched Iupac: … 2-[(4Z)-2-[(1S)-1-amino-3-(methylsulfanyl)propyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro- ... 1H-imidazol-1-yl]acetic acid …

Iodoxamic acid

Radiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Experimental
Matched Iupac: … 3-{1-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]-3,6,9,12-tetraoxapentadecan-15-amido}-2,4,6-triiodobenzoic …
Matched Salts cas: … 51764-33-1 …

Ioglycamic acid

Experimental

Xipamide

Experimental
Matched Iupac: … 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide …

Tesmilifene

Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Synonyms: … N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine …
Matched Iupac: … [2-(4-benzylphenoxy)ethyl]diethylamine …

Lucatumumab

Investigational

Heparan-N-sulfatase (human, recombinant)

Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Investigational

Beinaglutide

Beinaglutide is under investigation in clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus).
Investigational
Matched Categories: … Glucagon-like peptide-1 (GLP-1) analogues …

Humanized monoclonal antibody Hu11E6

Investigational

Dimepheptanol

Dimepheptanol is under investigation in clinical trial NCT00218127 (Treatment of Opioid/heroin Dependence: Comparison of Three Medication Dosing Regimens).
Investigational
Displaying drugs 10776 - 10800 of 13227 in total