Displaying drugs 10801 - 10825 of 11915 in total
Pozanicline
ABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity Disorder and Schizophrenia/Schizoaffective disorders. In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR...
Investigational
Matched Description: … ABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for …
CG0070
CG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. CG0070 can potentially destroy cancer cells by two different mechanisms: direct cell killing by the virus and immune-mediated cell killing stimulated by GM-CSF. CG0070, an oncolytic virus therapy with specificity for multiple cancers, has been evaluated...
Investigational
Matched Description: … CG0070 is a solid. …
Repinotan
Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Investigational
Matched Description: … Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective …
CAM-2029
CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the...
Investigational
Matched Description: … CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment ... CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant ... suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the target one-month therapeutic …
Interferon Kappa
Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide conserved in type I interferons. This gene encoding...
Investigational
Matched Description: … a 27-amino acid signal peptide conserved in type I interferons. ... Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino ... acids and has 30% homology with others of the same class as it consists of a series of cysteine and …
Latrunculin B
Latrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge Latrunculia magnifica.
Experimental
Matched Description: … Latrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge …
Solithromycin
Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Investigational
Matched Description: … Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired …
Navicixizumab
Navicixizumab is under investigation in clinical trial NCT02298387 (A Phase 1 Study of Navicixizumab in Subjects With Solid Tumors).
Investigational
Matched Description: … Navicixizumab is under investigation in clinical trial NCT02298387 (A Phase 1 Study of Navicixizumab …
Pegapamodutide
Pegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).
Investigational
Matched Description: … Pegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy …
TAS-116
TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).
Investigational
Matched Description: … TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid …
LY-2623091
LY-2623091 is under investigation in clinical trial NCT02194465 (A Study of LY2623091 in Participants With High Blood Pressure).
Investigational
Matched Description: … LY-2623091 is under investigation in clinical trial NCT02194465 (A Study of LY2623091 in Participants …
Centhaquine
Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock).
Investigational
Matched Description: … Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a …
E59
E59 is a humanized IgG1 low affinity allergic reactivity inhibiting (LARI) monoclonal antibody. It was developed by Sixal Inc.
Investigational
Matched Description: … E59 is a humanized IgG1 low affinity allergic reactivity inhibiting (LARI) monoclonal antibody. …
Epaminurad
Epaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).
Investigational
Matched Description: … Epaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of …
Rezpegaldesleukin
Rezpegaldesleukin is under investigation in clinical trial NCT04433585 (A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE)).
Investigational
Matched Description: … Rezpegaldesleukin is under investigation in clinical trial NCT04433585 (A Study of LY3471851 in Adults …
BNT162b1 SARS-CoV-2 Vaccine
BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Description: … BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a ... [L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding ... domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived …
LS11
LS11(talaporfin sodium) is an agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. It is used to treat many...
Investigational
Encenicline
Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.
Investigational
JNJ-27390467
JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.
Experimental
Matched Description: … JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase. …
Kebuzone
Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
Experimental
Matched Description: … Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug. …
Cloperastine
Cloperastine is a cough suppressant that acts on the central nervous system.
Experimental
Matched Description: … Cloperastine is a cough suppressant that acts on the central nervous system. …
Biomodulin T
Biomodulin T is a polypeptide fraction from bovine thymus with immunomodulatory effects.
Investigational
Matched Description: … Biomodulin T is a polypeptide fraction from bovine thymus with immunomodulatory effects. …
KT-333
KT-333 is a small molecule targeted protein degrader of STAT3.
Investigational
Matched Description: … KT-333 is a small molecule targeted protein degrader of STAT3.[L44086] …
MPB-1523
MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.
Investigational
Matched Description: … MPB-1523 is a contrast agent comprising PEGylated iron oxide nanoparticles.[L48161] …
rAAV9-hNAGLU
rAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase.
Investigational
Matched Description: … rAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase. …
Displaying drugs 10801 - 10825 of 11915 in total