Displaying drugs 10801 - 10825 of 12591 in total
Apaziquone
Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms.
Investigational
Matched Description: … Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms. …
Cenerimod
Cenerimod has been used in trials studying the treatment of Systemic Lupus Erythematosus.
Investigational
Matched Description: … Cenerimod has been used in trials studying the treatment of Systemic Lupus Erythematosus. …
Abituzumab
Abituzumab has been used in trials studying the treatment of Prostate Cancer Metastatic.
Investigational
Matched Description: … Abituzumab has been used in trials studying the treatment of Prostate Cancer Metastatic. …
Pancreatic Polypeptide
Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1.
Investigational
Matched Description: … Pancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1. …
Reproterol
Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
Investigational
Matched Description: … Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced. …
Omigapil
Omigapil has been used in trials studying the treatment of Congenital Muscular Dystrophy.
Investigational
Matched Description: … Omigapil has been used in trials studying the treatment of Congenital Muscular Dystrophy. …
GSK-1521498
GSK1521498 has been used in trials studying the treatment of Obesity and Alcoholism.
Investigational
Matched Description: … GSK1521498 has been used in trials studying the treatment of Obesity and Alcoholism. …
Torapsel
Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury.
Investigational
Matched Description: … Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury. …
S65487
S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.
Investigational
Matched Description: … S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746. …
VG161
VG161 is an oncolytic virus therapy under investigation for the treatment of cholangiocarcinoma.
Investigational
Matched Description: … VG161 is an oncolytic virus therapy under investigation for the treatment of cholangiocarcinoma. …
Chlormadinone acetate
Chlormadinone acetate is a progesterone derivative first synthesized in 1961. In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew...
Experimental
Withdrawn
Matched Description: … However, the use of these drugs was associated with the development of mammary tumors in dogs. ... In 1972, the FDA withdrew its approval for the use of chlormadinone acetate in all products. ... In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products …
AeroLEF
AeroLEF™ (aerosolized liposome-encapsulated fentanyl) is a novel, proprietary inhalation formulation of free and liposome-encapsulated fentanyl intended to provide rapid, extended and personalized analgesia for patients experiencing acute pain episodes. AeroLEF™ is in development for the treatment of moderate to severe pain, including cancer pain.
Investigational
Matched Description: … AeroLEF™ (aerosolized liposome-encapsulated fentanyl) is a novel, proprietary inhalation formulation of ... AeroLEF™ is in development for the treatment of moderate to severe pain, including cancer pain. …
INCB7839
INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways. It represents a potentially important new class of targeted breast cancer therapy. It has shown promising clinical activity in heavily pretreated, refractory breast cancer patients.
Investigational
Matched Description: … It represents a potentially important new class of targeted breast cancer therapy. ... INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of …
Neovastat
Neovastat is a naturally occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of action that provide broad therapeutic potential for a number of diseases. It is currently in international Phase III trials for renal cell carcinoma and non-small-cell lung cancer.
Investigational
Matched Description: … action that provide broad therapeutic potential for a number of diseases. ... occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of …
QRX-411
QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein. It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the USH2A gene.
Investigational
Matched Description: … It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ ... first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of …
PYM50018
PYM50018 is a patented, orally active, neuroprotective and neuroregenerative compound. It is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). In pre-clinical models, PYM50018 has been observed to protect against neuronal damage, increase neurite outgrowth, reverse oxidative damage and reverse neuronal apoptosis in...
Investigational
Matched Description: … When administered orally to a transgenic pre-clinical model of ALS, PYM50018 delays the loss of muscle ... It is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease …
Technetium Tc-99m ciprofloxacin
99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and tuberculosis. INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in...
Investigational
Matched Description: … agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound ... 99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging …
GS-441524
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir.[A203057,L13239] This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent.[A203057,A203057] GS-441524 continues to be studied in the treatment of Feline...
Experimental
Matched Description: … against a number of viruses, meaning GS-441524 is less potent. ... [L13775] _In vitro_ studies of GS-441524 have determined it has a higher EC50 than remdesivir ... [A203057,A203057] GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis …
MUC1 Dendritic Cell Vaccine
Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign...
Investigational
Matched Description: … Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the ... actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. ... antigens to the T-cells to initiate a primary response in the effector arm of the immune system. …
Rolicyclidine
Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.
Experimental
Illicit
Matched Description: … the Schedule I list of illegal drugs in the USA in the 1970s. ... Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to …
R1626
R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors. It achieves significant reductions in viral load in chronic hepatitis C patients infected with the difficult to treat genotype 1 virus. R1626 is very effective in inhibiting viral replication
Investigational
Matched Description: … R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors. …
IGN301
IGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).
Investigational
Matched Description: … Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. …
Thalagen
Thalagen is a branded product developed by San Rocco Therapeutics. It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene. It is being investigated for the treatment of beta-thalassemia.
Investigational
Matched Description: … It is being investigated for the treatment of beta-thalassemia.[L46168] ... It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral …
G207
G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG. These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. MediGene uses these viruses, however, in a modified and "disarmed" form in order to...
Investigational
Matched Description: … G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer ... These viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores …
CAM-2029
CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the...
Investigational
Matched Description: … a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of ... CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant ... suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the target one-month therapeutic …
Displaying drugs 10801 - 10825 of 12591 in total