Displaying drugs 10851 - 10875 of 12647 in total
Umbilical Cord Blood Hematopoietic Stem Cells
The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational
Matched Description: … The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive ... UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have ... This highlights the adaptive nature of these cells. …
SO-101
SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
Investigational
Matched Description: … SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected ... Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages …
Liposomal prostaglandin E1
Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent. The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways that PGE-1 alone could not achieve.
Investigational
Matched Description: … Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet ... The liposomal formulation of PGE-1 changes the drug’s dynamics and improve its therapeutic index in ways …
Amniotic Epithelial Cells
Amniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus.[A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine due to their potential for differentiation and multiplication.
Investigational
Matched Description: … the human amnion, the layer of the placenta closest to the fetus. ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of …
PA-1050040
PA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). It inhibits virus replication by the same mechanism of action as BVM.
Investigational
Matched Description: … It inhibits virus replication by the same mechanism of action as BVM. ... PA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). …
Paltusotine
Paltusotine is under investigation in clinical trial NCT04261712 (A Study to Evaluate the Long-term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)).
Investigational
Matched Description: … Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)). ... investigation in clinical trial NCT04261712 (A Study to Evaluate the Long-term Safety and Efficacy of …
Oxelumab
Oxelumab is under investigation in clinical trial NCT00983658 (A Study of HuMAb OX40L in the Prevention of Allergen-induced Airway Obstruction in Adults With Mild Allergic Asthma).
Investigational
Matched Description: … of Allergen-induced Airway Obstruction in Adults With Mild Allergic Asthma). ... Oxelumab is under investigation in clinical trial NCT00983658 (A Study of HuMAb OX40L in the Prevention …
AS1409
AS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and...
Investigational
Matched Description: … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma ... AS1409 is a genetically engineered fusion protein made up of two distinct components. …
CIGB-258 peptide
CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant. As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens...
Investigational
Matched Description: … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular ... As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the ... treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens …
Donanemab
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - pyroglutamate Aβ - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD). It works by inducing microglial-mediated clearance of existing Aβ...
Investigational
Matched Description: … [A232214] It works by inducing microglial-mediated clearance of existing Aβ plaques with the intent of ... the first trial with an expanded patient population in order to address some of the deficiencies of ... (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of …
Ferric pyrophosphate
Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate. It presents an increasing interest as this insoluble...
Experimental
Matched Description: … interactions of iron in plasma. ... side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Description: … NS3728 is an orally active chloride channel blocker for the treatment of cancer. …
Latrepirdine
Latrepirdine has been investigated for the treatment of Alzheimer's Disease and Huntington's Disease.
Investigational
Matched Description: … Latrepirdine has been investigated for the treatment of Alzheimer's Disease and Huntington's Disease. …
Censavudine
Censavudine has been used in trials studying the treatment of HIV-1 Infection.
Investigational
Matched Description: … Censavudine has been used in trials studying the treatment of HIV-1 Infection. …
Trehalose
Cabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy.
Investigational
Matched Description: … Cabaletta has been used in trials studying the treatment of Oculopharyngeal Muscular Dystrophy. …
Bemcentinib
Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.
Investigational
Matched Description: … Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer. …
Conbercept
Conbercept has been investigated for the basic science of Age-related Macular Degeneration.
Investigational
Matched Description: … Conbercept has been investigated for the basic science of Age-related Macular Degeneration. …
Perfluoro tert-butylcyclohexane
Oxycyte has been used in trials studying the treatment of Traumatic Brain Injury.
Investigational
Matched Description: … Oxycyte has been used in trials studying the treatment of Traumatic Brain Injury. …
Rimacalib
Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
Investigational
Matched Description: … Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA). …
Tedatioxetine
Tedatioxetine has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Description: … Tedatioxetine has been used in trials studying the treatment of Major Depressive Disorder. …
MSX-122
MSX-122 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Description: … MSX-122 has been used in trials studying the treatment of Solid Tumors. …
Rontalizumab
Rontalizumab has been used in trials studying the treatment of Systemic Lupus Erythematosus.
Investigational
Matched Description: … Rontalizumab has been used in trials studying the treatment of Systemic Lupus Erythematosus. …
Glucose oxidase
Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.
Investigational
Matched Description: … Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections. …
MK-7622
MK-7622 has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Description: … MK-7622 has been used in trials studying the treatment of Alzheimer's Disease. …
TT-301
TT301 has been used in trials studying the treatment of Traumatic Brain Injury.
Investigational
Matched Description: … TT301 has been used in trials studying the treatment of Traumatic Brain Injury. …
Displaying drugs 10851 - 10875 of 12647 in total