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Displaying drugs 11126 - 11150 of 11952 in total
OSI-930
OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
Matched Iupac: … 3-{[(quinolin-4-yl)methyl]amino}-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide …
Dimethylcurcumin
Dimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.
Investigational
Matched Iupac: … (1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one …
Pirodavir
Pirodavir is an antipicornavirus agent.
Experimental
Matched Iupac: … ethyl 4-{2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy}benzoate …
Ramosetron
Ramosetron is a serotonin 5-HT3 receptor antagonist commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Currently, ramosetron is only approved for use Japan and in...
Investigational
Matched Iupac: … (5R)-5-(1-methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole …
Matched Salts cas: … 132907-72-3 …
Matched Salts cas: … 132907-72-3 …
AZD-0328
AZD0328 has been used in trials studying the treatment and basic science of Schizophrenia and Alzheimer's Disease.
Investigational
Matched Iupac: … (2R)-3'H-4-azaspiro[bicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine] …
Cicletanine
Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
Investigational
Matched Iupac: … 3-(4-chlorophenyl)-6-methyl-1H,3H-furo[3,4-c]pyridin-7-ol …
GSI-136
GSI-136 has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … 5-chloro-N-[(2S)-3-ethyl-1-hydroxypentan-2-yl]thiophene-2-sulfonamide …
Idanpramine
Experimental
Matched Iupac: … 5,5-bis(4-methoxyphenyl)-3-[2-(piperidin-1-yl)ethyl]imidazolidine-2,4-dione …
Epanolol
Epanolol is an beta blocker.
Experimental
Matched Iupac: … N-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-2-(4-hydroxyphenyl)acetamide …
Flufenoxuron
Flufenoxuron is under investigation in clinical trial NCT00922870 (Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock).
Investigational
Matched Iupac: … 1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}-3-(2,6-difluorobenzoyl)urea …
Pyridoxamine-5'-Phosphate
Experimental
Matched Iupac: … {[4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methoxy}phosphonic acid …
Pyridoxine phosphate
Experimental
Matched Iupac: … {[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy}phosphonic acid …
Lpc-Ether
Experimental
Matched Iupac: … [(2R)-2-hydroxy-3-(octadecyloxy)propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …
Naluzotan
Investigational
Matched Iupac: … N-(3-{4-[4-(cyclohexylmethanesulfonamido)butyl]piperazin-1-yl}phenyl)acetamide …
Levopropoxyphene
Levopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. This drug presented different dosages and it was administered...
Withdrawn
Matched Iupac: … (2R,3S)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
CYCLOHEXYL-NORSTATINE
Experimental
Matched Iupac: … propan-2-yl (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutanoate …
Decoquinate
Decoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Experimental
Vet approved
Matched Iupac: … ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Talsaclidine
Talsaclidine has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … (3R)-3-(prop-2-yn-1-yloxy)-1-azabicyclo[2.2.2]octane …
Liarozole
Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Investigational
Matched Iupac: … 6-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-1,3-benzodiazole …
Tiropramide
Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
Investigational
Matched Iupac: … 3-{4-[2-(diethylamino)ethoxy]phenyl}-2-(phenylformamido)-N,N-dipropylpropanamide …
Benzilone
Experimental
Matched Iupac: … 1,1-diethyl-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]pyrrolidin-1-ium …
Prenoxdiazine
Experimental
Matched Iupac: … 1-{2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl}piperidine …
Etybenzatropine
Experimental
Matched Iupac: … (1R,3S,5S)-3-(diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane …
Oxantel
Experimental
Matched Iupac: … 3-[(E)-2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)ethenyl]phenol …
Displaying drugs 11126 - 11150 of 11952 in total