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Displaying drugs 11226 - 11250 of 13992 in total
Vixotrigine
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Investigational
Matched Iupac: … (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide …
Matched Salts cas: … 934240-31-0 …
Matched Salts cas: … 934240-31-0 …
Tea tree oil
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
N-Succinyl Phenylglycine
Experimental
Matched Iupac: … 3-{[(R)-carboxy(phenyl)methyl]carbamoyl}propanoic acid …
N-Propargyl-1(S)-Aminoindan
Experimental
Matched Name: … N-Propargyl-1(S)-Aminoindan …
Matched Iupac: … (1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Matched Iupac: … (1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Heat stable ricin vaccine
Heat stable ricin vaccine is an alum-adjuvanted, heat stable recombinant subunit vaccine.
Investigational
Sacituzumab tirumotecan
Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.
Investigational
Simoladagene autotemcel
Investigational
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Iupac: … [(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4Z)-4-(hydroxyimino)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2 ... -yl]methyl 2-methylpropanoate …
Matched Description: … non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’ ... studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, …
Matched Description: … non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’ ... studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, …
Dexrabeprazole
Experimental
Matched Iupac: … 2-[(R)-[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles …
Clocortolone caproate
Experimental
Matched Iupac: … 2-[(1S,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-9b-chloro-5-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H ... ,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl hexanoate …
Camazepam
Camazepam is a benzodiazepine which is a dimethyl carbamate ester of tamzepam, a metabolite of diazepam. Similarly to other drugs in its class, it has antxiolytic, anticonvulsant, hypnotic, and skeletal muscle relaxant properties. However, unlike other benzodiapeines camazepam is predominantly anxiolytic and is relatively weak as an anticonvulsant, hypnotic and...
Experimental
Illicit
Matched Iupac: … 7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl N,N-dimethylcarbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Brequinar
Experimental
Matched Iupac: … 6-fluoro-2-{2'-fluoro-[1,1'-biphenyl]-4-yl}-3-methylquinoline-4-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Motesanib
Investigational
Matched Iupac: … N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Matched Salts cas: … 857876-30-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 857876-30-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
TAK-901
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
Investigational
Matched Iupac: … 5-[3-(ethanesulfonyl)phenyl]-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Efloxate
Experimental
Matched Iupac: … ethyl 2-[(4-oxo-2-phenyl-4H-chromen-7-yl)oxy]acetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Doxefazepam
Experimental
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-(2-hydroxyethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GS-6620
GS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis C Virus Infection).
Investigational
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}-5-cyano-4-hydroxy ... -4-methyl-3-[(2-methylpropanoyl)oxy]oxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Chiauranib
Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).
Investigational
Matched Iupac: … N-(2-aminophenyl)-6-[(7-methoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Hematoxylin
Investigational
Matched Iupac: … (1R,10S)-8-oxatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12,14,16-hexaene-5,6,10,14,15-pentol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pixofisiran
Investigational
Tridihexethyl
Tridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Tridihexethyl is an antimuscarinic, anticholinergic drug. Tridihexethyl is no longer available in the US market.
Withdrawn
Matched Iupac: … (3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylazanium …
Calcitonin gene-related peptide
A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes...
Investigational
Terevalefim
Terevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).
Investigational
Matched Iupac: … 3-[(1E)-2-(thiophen-2-yl)ethenyl]-1H-pyrazole …
O-(N-acetyl-alpha-D-galactosaminyl)-L-serine
Experimental
Matched Iupac: … (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic …
Lesinidase alfa
Lesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)).
Investigational
Displaying drugs 11226 - 11250 of 13992 in total