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Displaying drugs 11401 - 11425 of 13650 in total

Bisindolylmaleimide I

Experimental
Matched Iupac: … 3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Cediranib

The novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment of cancer.
Investigational
Matched Iupac: … 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline …
Matched Description: … The novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive …
Matched Salts cas: … 857036-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Indirubin

Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Investigational
Matched Iupac: … (E)-1',2'-dihydro-1H,3H-[2,3'-biindolylidene]-2',3-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bindarit

Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Investigational
Matched Iupac: … 2-[(1-benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Ensitrelvir

Ensitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections &amp; Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

1-Phenylcyclohexylamine

Experimental
Illicit
Matched Name: … 1-Phenylcyclohexylamine …
Matched Iupac: … 1-phenylcyclohexan-1-amine …

N-Propargyl-1(S)-Aminoindan

Experimental
Matched Name: … N-Propargyl-1(S)-Aminoindan …
Matched Iupac: … (1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …

16-Bromoepiandrosterone

16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide. It is a chemical relative of DHEA which was selected for development after it showed antiretroviral activity in laboratory tests.
Investigational
Matched Iupac: … -1-one ... (2R,3aS,3bR,5aS,7S,9aS,9bS,11aS)-2-bromo-7-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren …

Methoxy PEG-12 retinamide

Experimental

1-naphthaleneacetic acid

Experimental
Matched Synonyms: … 1-Naphthylacetic acid ... naphthalene-1-acetic acid ... naphthalen-1-yl-acetic acid …
Matched Name: … 1-naphthaleneacetic acid …
Matched Iupac: … 2-(naphthalen-1-yl)acetic acid …

Rhenium (186-Re) obisbemeda

Investigational
Matched Iupac: … (2-{[2-(diethylamino)ethyl](2-sulfanidylethyl)amino}ethyl)sulfanide; (2-{[2-(diethylamino)ethyl](2-sulfanylethyl …

Edivoxetine

Edivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant treatment. Edivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012.
Investigational
Matched Iupac: … (1R)-2-(5-fluoro-2-methoxyphenyl)-1-[(2S)-morpholin-2-yl]-1-(oxan-4-yl)ethan-1-ol …
Matched Salts cas: … 1194374-05-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Chlorophyll B

A light, silvery, metallic element. It has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. Its salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. It is a component of both intra- and extracellular fluids and is...
Experimental
Matched Iupac: … magnesium(2+) (3R,21S,22S)-16-ethenyl-11-ethyl-12-formyl-3-(methoxycarbonyl)-17,21,26-trimethyl-4-oxo ... -22-(3-oxo-3-{[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy}propyl)-7,23,24,25-tetraazahexacyclo ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaene …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …

Izokibep

Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).
Investigational
Matched Synonyms: … FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM …

Matrix-M

Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.
Investigational

Tiemonium iodide

Experimental
Matched Iupac: … 4-[3-hydroxy-3-phenyl-3-(thiophen-2-yl)propyl]-4-methylmorpholin-4-ium iodide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Recombinant human palmitoyl-protein thioesterase-1

Investigational
Matched Synonyms: … Recombinant human palmitoyl-protein thioeserase-1 ... RECOMBINANT HUMAN PALMITOYL-PROTEIN THIOESERASE-1 (RHPPT1) …
Matched Name: … Recombinant human palmitoyl-protein thioesterase-1 …

Cycloleucine

Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
Experimental
Matched Synonyms: … 1-amino-1-cyclopentanecarboxylic acid ... 1-aminocyclopentane-1-carboxylic acid ... 1-aminocyclopentanecarboxylic acid …
Matched Iupac: … 1-aminocyclopentane-1-carboxylic acid …

Coblopasvir

Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).
Investigational
Matched Iupac: … -2-yl]-1H-imidazol-5-yl}-2H-1,3-benzodioxol-4-yl)phenyl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1 ... methyl N-[(2S)-1-[(2S)-2-{5-[4-(7-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... -oxobutan-2-yl]carbamate …

p1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate

Experimental
Matched Iupac: … -1-yl)oxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy})phosphinic acid ... ](hydroxy)phosphoryl}oxy)({[hydroxy({[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin ... ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …

Moxaverine

Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
Investigational
Matched Iupac: … 1-benzyl-3-ethyl-6,7-dimethoxyisoquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bietaserpine

Experimental
Matched Iupac: … methyl (1R,15S,17R,18R,19S,20S)-3-[2-(diethylamino)ethyl]-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy ... )-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Fosfructose

Experimental
Matched Iupac: … {[(3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
Matched Salts cas: … 81028-91-3 …

Beclabuvir

Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Investigational
Matched Iupac: … (8S,10R)-19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]octane ... -8-carbonyl]-12-azapentacyclo[10.7.0.0^{2,7}.0^{8,10}.0^{13,18}]nonadeca-1(19),2,4,6,13,15,17-heptaene …
Matched Salts cas: … 958002-36-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

p-Chlorobenzoic acid

Experimental
Matched Synonyms: … 4-chlorobenzoic acid …
Matched Iupac: … 4-chlorobenzoic acid …
Displaying drugs 11401 - 11425 of 13650 in total