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Displaying drugs 1126 - 1150 of 1866 in total
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … Guanosine 3',5'-cyclic phosphate
Matched Description: … and it has been found to activate specific protein kinases. ... is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide ... 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Description: … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indoles
Carya ovata pollen is the pollen of the Carya ovata plant. Carya ovata pollen is mainly used in allergenic testing.
Approved
Matched Name: … Carya ovata pollen …
Matched Description: … Carya ovata pollen is the pollen of the Carya ovata plant. ... Carya ovata pollen is mainly used in allergenic testing. …
Matched Products: … Carya Ovata Pollen ... Center-AL - Carya Ovata Pollen ... Pollens - Trees, Hickory, Shagbark Carya ovata …
Carya cordiformis pollen is the pollen of the Carya cordiformis plant. Carya cordiformis pollen is mainly used in allergenic testing.
Approved
Matched Name: … Carya cordiformis pollen …
Matched Description: … Carya cordiformis pollen is the pollen of the Carya cordiformis plant. ... Carya cordiformis pollen is mainly used in allergenic testing. …
Carya laciniosa pollen allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Carya laciniosa pollen …
Matched Name: … Carya laciniosa pollen …
Matched Description: … Carya laciniosa pollen allergenic extract is used in allergenic testing. …
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl ... 6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline ... chloro-2-fluorophenyl)-1'-ethyl-1'',2''-dihydro-2''-oxodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-(3h)indol
Matched Iupac: … -chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody
Investigational
Matched International brands: … Cardio Vascu-Grow …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid …
Matched Description: … and then reabsorbed from the intestines. ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and ... levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Indian frankincense is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Boswellia Glabra Resin …
Matched Mixtures name: … Oil
Etofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
Experimental
Matched Description: … Etofenamate is used to treat muscle and joint paint. …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … INDOREX-SAN …
HPA-23 is an investigational antiviral compound.
Investigational
Matched Synonyms: … Ammonium antimony sodium tungsten oxide ((nh4)17sb9na2w21o86) …
Investigational
Matched Synonyms: … (3s)-3-(6-((4-(morpholin-4-ylmethyl)phenyl)methyl)-2-oxobenzo(cd)indol-1-yl)piperidine-2,6-dione ... 2,6-piperidinedione, 3-(6-((4-(4-morpholinylmethyl)phenyl)methyl)-2-oxobenz(cd)indol-1(2h)-yl)-, (3s) …
For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Investigational
Nutraceutical
Matched Synonyms: … 3-(2-Aminoethyl)-1H-indol-5-ol …
Matched Iupac: … 3-(2-aminoethyl)-1H-indol-5-ol …
Matched Description: … For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and
Matched Categories: … Indoles
Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Description: … first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and ... increase the number and sensitivity of insulin receptors. ... efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … GLICLAZIDE GENTIAN GENERICS ... GLICLAZIDE EG STADA ... GLICLAZIDE EG STADA ITALIA …
Investigational
Matched Synonyms: … Anti-bcma antibody sea-bcma ... Nonfucosylated humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting B-cell maturation antigen …
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
Investigational
Matched Synonyms: … Antimelanoma antibody XMMME-001-RTA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
Investigational
Matched Synonyms: … Anti-globo h monoclonal antibody obi-888 …
Investigational
Matched Synonyms: … Anti-interleukin-7 Receptor α Monoclonal antibody
CN-201 is a humanized anti-CD3/CD19 bispecific antibody.
Investigational
Matched Synonyms: … recombinant humanized anti-CD3/CD19 bispecific antibody
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Experimental
Matched Name: … indane-5-sulfonamide …
Matched Iupac: … 2,3-dihydro-1H-indene-5-sulfonamide …
Experimental
Matched Name: … 2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(3-methylphenyl)-1H-indole-5-carboximidamide …
Displaying drugs 1126 - 1150 of 1866 in total