Displaying drugs 11551 - 11575 of 12743 in total
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]benzamido}-N-[5-({5-[(2-carbamimidoylethyl)carbamoyl]-1-methyl-1H-pyrrol ... -3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide …
Matched Salts cas: … 118438-45-2 …
Matched Salts cas: … 118438-45-2 …
1-Beta-Ribofuranosyl-1,3-Diazepinone
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3-dihydro-1H-1,3-diazepin-2-one …
LY-517717
LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
Seviteronel
Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Investigational
Matched Iupac: … (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(1H-1,2,3-triazol-5-yl)propan-1-ol …
Vofopitant
Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … (2S,3S)-N-({2-methoxy-5-[5-(trifluoromethyl)-1H-1,2,3,4-tetrazol-1-yl]phenyl}methyl)-2-phenylpiperidin …
Ranimustine
Experimental
Matched Iupac: … 3-(2-chloroethyl)-3-nitroso-1-{[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl}urea …
Eltanexor
Eltanexor is under investigation in clinical trial NCT02649790 (Study of the Safety, Tolerability and Efficacy of KPT-8602 in Patients With Relapsed/refractory Cancer Indications).
Investigational
Matched Iupac: … (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)prop-2-enamide …
Ampiroxicam
Investigational
Matched Iupac: … ethyl 1-({2-methyl-1,1-dioxo-3-[(pyridin-2-yl)carbamoyl]-2H-1lambda6,2-benzothiazin-4-yl}oxy)ethyl carbonate …
S-Hydroxycysteine
S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. It targets the proteins subtilisin BPN', glutathione S-transferase A1,...
Experimental
Matched Iupac: … (2R)-2-amino-3-(hydroxysulfanyl)propanoic acid …
S-Methyl Thiocysteine Group
Experimental
Matched Iupac: … (2R)-2-amino-3-(methyldisulfanyl)propanoic acid …
L-methionine (S)-S-oxide
Experimental
Matched Iupac: … (2S)-2-azaniumyl-4-[(S)-methanesulfinyl]butanoate …
Phenylalanine-N-Sulfonamide
Experimental
Matched Iupac: … (2S)-3-phenyl-2-(sulfamoylamino)propanoic acid …
N-Carbamyl-D-Methionine
Experimental
Matched Iupac: … (2R)-2-(carbamoylamino)-4-(methylsulfanyl)butanoic acid …
sn-glycero-3-phosphoethanolamine
Experimental
Matched Iupac: … (2-aminoethoxy)[(2S)-2,3-dihydroxypropoxy]phosphinic acid …
Dexfosfoserine
The phosphoric acid ester of serine.
Experimental
Matched Iupac: … (2S)-2-amino-3-(phosphonooxy)propanoic acid …
N-BENZYLOXYCARBONYL-L-SERINE-BETALACTONE
Experimental
Matched Iupac: … (2S)-2-{[(benzyloxy)carbonyl]amino}propanoic acid …
Acridine Carboxamide
Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … N-[2-(dimethylamino)ethyl]acridine-4-carboxamide …
T-900607
T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
Investigational
Matched Iupac: … [2-methoxy-5-(2,3,4,5,6-pentafluorobenzenesulfonamido)phenyl]urea …
Displaying drugs 11551 - 11575 of 12743 in total