Vofopitant

DB12436InvestigationalSmall molecule

Vofopitant has been used in trials studying the treatment of PTSD, Primary Insomnia, and Sleep Initiation and Maintenance Disorders.

Chemical structure of Vofopitant
Mechanism
Curator reviewed
Formula / weight
C21H23F3N6O · 432.451 g/mol (avg)
Code names
GR-205171

Resolves to

Compound
UNIIK08BK043YSCAS168266-90-8ChEMBLCHEMBL522302PubChem6918331
Structure
InChIKeyXILNRORTJVDYRH-HKUYNNGSSA-NSMILESCOC1=CC=C(C=C1CN[C@H]1CCCN[C@H]1C1=CC=CC=C1)N1N=NN=C1C(F)(F)F
Targets
P25103TACR1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Vofopitant, and which of those have an active Phase 3 trial?

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