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Displaying drugs 11551 - 11575 of 13223 in total
Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Investigational
Matched Iupac: … ethyl 2-{[(7S)-7-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydronaphthalen-2-yl]oxy …
Matched Salts cas: … 121524-09-2
Dalcetrapib is under investigation for the treatment of Acute Coronary Syndrome.
Investigational
Matched Iupac: … 1-(2-ethylbutyl)-N-{2-[(2-methylpropanoyl)sulfanyl]phenyl}cyclohexane-1-carboxamide …
Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Iupac: … ethyl 2-{N-methyl-2-[5-(tetradecyloxy)furan-2-carbonyloxy]acetamido}acetate …
Experimental
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 2-ethoxyacetate …
Experimental
Matched Iupac: … 2-[bis(butan-2-yl)amino]-1-{1-[(2-chlorophenyl)methyl]-1H-pyrrol-2-yl}ethan-1-ol …
Omiganan has been investigated for the treatment of Mupirocin-resistant MRSA skin infections.
Investigational
Matched Iupac: … -2-yl]formamido}-3-(1H-indol-3-yl)propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido ... ,3S)-2-amino-3-methylpentanamido]-4-methylpentanamido]-5-carbamimidamidopentanamido]-3-(1H-indol-3-yl ... (2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S ... )propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-indol-3-yl)propanamido]-3-(1H-indol-3-yl)propanoyl]pyrrolidin …
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido ... ]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanamido]-4-methylpentanoic acid ... ]-4-(methylsulfanyl)butanamido]-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]propanoyl …
Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … 2-{[(2S,4S)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl}ethane-1-sulfonic …
Granotapide has been used in trials studying the treatment of Type II Diabetes Mellitus.
Investigational
Matched Iupac: … 1,3-diethyl 2-[({2-[3-(dimethylcarbamoyl)-4-[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido]phenyl]acetyl ... }oxy)methyl]-2-phenylpropanedioate …
Vicagrel is under investigation in clinical trial NCT03599284 (The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel).
Investigational
Matched Iupac: … methyl (2S)-2-[2-(acetyloxy)-4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl]-2-(2-chlorophenyl)acetate …
Experimental
Matched Iupac: … (2R)-2-phenyl-2-sulfoacetic acid …
Iodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults).
Investigational
Matched Iupac: … 2-[(2-iodophenyl)formamido]acetic acid …
Experimental
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride …
Experimental
Matched Iupac: … 2-{4-[(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl}acetamide …
Experimental
Matched Iupac: … 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-[(oxolan-2-yl)methyl]propanoate …
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Lobaplatin has been used in trials studying the treatment of Breast Cancer, Hepatocellular Carcinoma, and Lobaplatin and Gemcitabine in Combination, Second-line Treatments on Advanced Osteosarcoma.
Investigational
Matched Iupac: … platinum(2+) 1-[(1R,2R)-2-(aminomethyl)cyclobutyl]methanamine (2S)-2-oxidopropanoate …
Experimental
Matched Iupac: … ({1-[2-(2-chlorobenzoyl)-4-nitrophenyl]-1H-imidazol-2-yl}methyl)diethylamine …
Experimental
Matched Iupac: … 1-{2-[(2-chlorophenyl)(phenyl)methoxy]ethyl}-4-[(2-methylphenyl)methyl]piperazine …
Experimental
Matched Iupac: … 2-(dimethylamino)ethyl 2,2-diphenyl-2-(prop-2-yn-1-yloxy)acetate …
Filorexant has been used in trials studying the prevention and treatment of Migraine, Headache, Polysomnography, Diabetic Neuropathy, Painful, and Major Depressive Disorder, Recurrent.
Investigational
Matched Iupac: … 2-{2-[(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidine-1-carbonyl]-4-methylphenyl}pyrimidine …
A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)
Illicit
Withdrawn
Matched Iupac: … 1-(4-chlorophenyl)-2-methylpropan-2-amine …
Experimental
Matched Iupac: … (2S)-2-amino-2-carboxyethan-1-aminium …
ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective...
Investigational
Matched Iupac: … (2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-{[(2S)-1-acetylpyrrolidin-2-yl]formamido}-3-(1H-imidazol-5-yl)propanamido …
Matched Description: … ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. ... Since the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor …
Experimental
Displaying drugs 11551 - 11575 of 13223 in total