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Displaying drugs 11701 - 11725 of 12530 in total
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Iupac: … (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-3H-spiro[2-benzofuran-1,2'-oxane]-3 ... ',4',5'-triol …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2. …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl ... )phenyl]-1,2-dihydropyridine-3-carboxamide …
Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … {[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}[2-(decyloxy ... )-3-(dodecylsulfanyl)propoxy]phosphinic acid …
Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).
Investigational
Matched Iupac: … (2R,3R,11bR)-9-[3-(¹⁸F)fluoropropoxy]-10-methoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1 ... -a]isoquinolin-2-ol …
Timcodar has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S)-N-benzyl-N-[1,5-bis(pyridin-4-yl)pentan-3-yl]-3-(4-chlorophenyl)-2-[N-methyl-2-oxo-2-(3,4,5-trimethoxyphenyl …
BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).
Investigational
Matched Iupac: … 1-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3- ... (2-hydroxy-2-methylpropyl)urea …
Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Investigational
Matched Iupac: … (2S,3S)-3-[(5-fluoro-2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-4-yl)amino]bicyclo[2.2.2]octane ... -2-carboxylic acid …
UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. Plasmepsins are aspartyl proteases produced by the malaria parasite Plasmodium falciparum, and PMX is considered to be essential for parasite egress and invasion. UCB7362 is estimated to achieve a significant reduction in asexual blood-stage...
Investigational
Matched Iupac: … N-{2-chloro-3-[(4S)-2-imino-4-methyl-1-[(2S,4S)-2-methyloxan-4-yl]-6-oxo-1,3-diazinan-4-yl]phenyl}-3- …
Thymopentin has been used in trials studying the treatment and prevention of HIV Infections and Hepatocellular Carcinoma.
Investigational
Matched Iupac: … (3S)-3-[(2S)-6-amino-2-[(2S)-2-amino-5-[(diaminomethylidene)amino]pentanamido]hexanamido]-3-[(1-{[(1S ... )-1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-methylpropyl)carbamoyl]propanoic acid …
Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).
Investigational
Matched Iupac: … (1r,1'R,4R)-4-methoxy-5''-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-indene ... -1',2''-imidazol]-4''-amine …
Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is...
Investigational
Withdrawn
Matched Iupac: … 4-[(2S)-3-(4-hydroxyphenyl)-2-(phenylformamido)propanamido]benzoic acid …
Experimental
Matched Iupac: … (3R,4R)-3-(4-hydroxybenzamido)azepan-4-yl 4-hydroxybenzoate …
AR-9281 inhibits soluble epoxide hydrolase.
Investigational
Matched Iupac: … 1-(1-acetylpiperidin-4-yl)-3-(adamantan-1-yl)urea …
Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.
Experimental
Matched Iupac: … 2-(pyridine-3-carbonyloxy)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Experimental
Matched Iupac: … 3-phenyl-7-(propan-2-yloxy)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-{[(methylcarbamoyl)methyl]carbamoyl}benzoic acid …
D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety, Tolerability and Diagnostic Performance of BAY86-9596 in Patients With Non-small Cell Lung Cancer, Breast Cancer, Head and Neck Cancer and Patients With Inflammations).
Investigational
Matched Iupac: … (2R)-2-amino-3-{4-[(¹⁸F)fluoromethoxy]phenyl}propanoic acid …
Experimental
Matched Iupac: … 2-(4-methylcyclohex-3-en-1-yl)propan-2-ol …
Landipirdine is under investigation in clinical trial NCT02258152 (SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)).
Investigational
Matched Iupac: … {[(1R)-6-(3-fluorobenzenesulfonyl)-1,2,3,4-tetrahydronaphthalen-1-yl]methyl}urea …
Experimental
Matched Iupac: … -methylbutyl)carbamoyl]pentyl}carbamoyl)-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-3-methylbutyl)carbamoyl ... 4-[(1-{[1-({5-amino-1-[(1-{[1-({1-[(1-{2-[(4-carbamimidamido-1-{[1-({1-[(1-{[({1-[({[1-(2-carbamoylpyrrolidin ... -hydroxyphenyl)-1-oxopropan-2-yl)carbamoyl]-2-hydroxypropyl}carbamoyl)-3-carbamoylpropyl]carbamoyl}-3 ... ]-4-(2-{2-[2-(6-amino-2-{2-[2-(2-{[3-amino-6-(carbamoylmethyl)-15-(1-hydroxyethyl)-12-(hydroxymethyl) ... )carbamoyl]-2-carboxyethyl}carbamoyl)-2-hydroxypropyl]carbamoyl}butyl)carbamoyl]pyrrolidin-1-yl}-3-(4 …
Experimental
Matched Iupac: … (2S)-3-{[(2S)-2,3-dihydroxypropyl phosphonato]oxy}-2-hydroxypropyl hexadecanoate …
Experimental
Matched Iupac: … 2,6-bis(3-carbamimidoylphenoxy)-3,5-difluoro-4-methylpyridin-1-ium …
Experimental
Matched Iupac: … 2-[(2R)-2-{[(benzyloxy)carbonyl]amino}-3-sulfanylpropanamido]acetic acid …
Vet approved
Matched Iupac: … 2-[(phenylcarbamoyl)oxy]-3-(piperidin-1-yl)propyl N-phenylcarbamate …
Matched Salts cas: … 537-12-2
Experimental
Matched Iupac: … N'-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}ethoxycarbohydrazide …
Displaying drugs 11701 - 11725 of 12530 in total