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Displaying drugs 11751 - 11775 of 12530 in total
Pexmetinib
Pexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
Investigational
Matched Iupac: … 3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-[(5-fluoro-2-{[1-(2-hydroxyethyl)-1H-indazol-5- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
IDRX-42
Investigational
Matched Iupac: … -3-yl}pyrimidin-4-amine ... N-{[4-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-6-{7-[3-(pyrrolidin-1-yl)propoxy]imidazo[1,2-a]pyridin …
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Lactobacillus brevis
Investigational
Trypanothione
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-{[({3-[(4-{2-[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-3-sulfanylpropanamido ... ]acetamido}butyl)amino]propyl}carbamoyl)methyl]carbamoyl}-2-sulfanylethyl]carbamoyl}butanoic acid …
GS-9191
GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts).
Investigational
Matched Iupac: … )-1-oxo-3-phenylpropan-2-yl]amino})phosphoryl]amino}-3-phenylpropanoate ... 2-methylpropyl (2S)-2-{[({2-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]ethoxy}methyl)({[(2S)-1-(2-methylpropoxy …
Zimberelimab
Investigational
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Iupac: … (2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nelivaptan
Nelivaptan has been used in trials studying the treatment of Anxiety Disorders, Depressive Disorder, and Major Depressive Disorder.
Investigational
Matched Iupac: … (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxybenzenesulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol ... -3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
TAS-117
TAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).
Investigational
Matched Iupac: … (1r,3s)-3-amino-1-methyl-3-(4-{5-phenyl-8-oxa-3,6,12-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2,4,9,11 …
Lodenafil carbonate
Lodenafil carbonate has been used in trials studying the treatment of Coronaropathy and Erectile Dysfunction.
Investigational
Matched Iupac: … bis{2-[4-(4-ethoxy-3-{1-methyl-7-oxo-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}benzenesulfonyl) …
Naquotinib
Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor (EGFR) Mutations, among others.
Investigational
Matched Iupac: … 6-ethyl-3-({4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-{[(3R)-1-(prop-2-enoyl)pyrrolidin ... -3-yl]oxy}pyrazine-2-carboxamide …
Matched Salts cas: … 1448237-05-5 …
Matched Salts cas: … 1448237-05-5 …
TAS-116
TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).
Investigational
Matched Iupac: … 3-ethyl-4-{4-[4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-3-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin …
Indium
Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma.
Investigational
Matched Salts cas: … 25114-58-3 …
Dinor-N(Omega)-Hydroxy-L-Arginine
Experimental
Matched Iupac: … (2S)-2-amino-3-[(E)-[amino(hydroxyamino)methylidene]amino]propanoic acid …
Ethylaminobenzylmethylcarbonyl Group
Experimental
Matched Iupac: … (2S)-2-[(3R)-3-benzyl-2-oxopiperazin-1-yl]hexanoic acid …
Clorgiline
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Iupac: … [3-(2,4-dichlorophenoxy)propyl](methyl)(prop-2-yn-1-yl)amine …
Matched Salts cas: … 17780-75-5 …
Matched Salts cas: … 17780-75-5 …
Firocoxib
Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. It currently approved for veterinary use in dogs and horses under the brand names Equioxx and Previcox. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. Firocoxib is not intended or approved for use...
Experimental
Vet approved
Matched Iupac: … 3-(cyclopropylmethoxy)-4-(4-methanesulfonylphenyl)-5,5-dimethyl-2,5-dihydrofuran-2-one …
Matched Description: … Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. ... Firocoxib was the first COX-2 inhibitor approved by the U.S. …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Description: … Firocoxib is a cycooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug. ... Firocoxib was the first COX-2 inhibitor approved by the U.S. …
Matched Categories: … Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Nequinate
Nequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. These are compounds containing an hydrogenated quinoline bearing a ketone group.
Vet approved
Matched Iupac: … methyl 7-(benzyloxy)-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ractopamine
Vet approved
Matched Iupac: … 4-(3-{[2-hydroxy-2-(4-hydroxyphenyl)ethyl]amino}butyl)phenol …
Arhalofenate
Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia.
Investigational
Matched Iupac: … 2-acetamidoethyl (2R)-2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetate …
Indirubin
Indirubin is under investigation in clinical trial NCT01735864 (Dosage Determination Trial for Indigo Naturalis Extract in Oil Ointment).
Investigational
Matched Iupac: … (E)-1',2'-dihydro-1H,3H-[2,3'-biindolylidene]-2',3-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bindarit
Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Investigational
Matched Iupac: … 2-[(1-benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Feprazone
Experimental
Matched Iupac: … 4-(3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Categories: … Non COX-2 selective NSAIDS …
Displaying drugs 11751 - 11775 of 12530 in total