Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 1176 - 1200 of 1544 in total

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ไอริน็อกซ์ 100 ... IRINOCAN 100 CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/ 5 ML ... TARCKORIN ® 100MG …

Oxaliplatin

Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Description: … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. ... refractory to an initial fluorouracil and leucovorin combination. ... [A260396] The DACH moiety also prevents cross-resistance with cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXPLAR ® 100 ... CRISAPLA® 100 ... OXALIPRO 100 MG …

Buloxibutid

Investigational
Matched Synonyms: … butyl [3-{4-[(1H-imidazol-1-yl)methyl]phenyl}-5-(2-methylpropyl)thiophene-2-sulfonyl]carbamate …
Matched Iupac: … butyl N-[(3-{4-[(1H-imidazol-1-yl)methyl]phenyl}-5-(2-methylpropyl)thiophen-2-yl)sulfonyl]carbamate …

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … PRECEDEX® 400MCG/100ML (4MCG/ML) ... REDEXA ® DEXMEDETOMIDINA 100 MCG /ML POR 2 ML ... SEMOTİDİN 400 MCG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically ... spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … นูคาล่า (100 มก.) ... NUCALA® 100MG/ML SOLUCION INYECTABLE ... NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg …

Paclitaxel

Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … แพคลิเทอโร 100 ... ALZENE 100 MG ... PAXUS PM (100 MG) …

Alanyl glutamine

Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … DIPEPTIVEN 100 ML SOLUSYON ... DIPEPTIVEN INFUSION (50ML, 100ML GLASS BOTTLE) ... DİPEPİTVEN %20 İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ, 100 ML …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Salts name: … Chloroquine sulfate …
Matched Categories: … chloroquine and proguanil ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 1000 ADET …

Anagrelide

Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Description: … [busulfan], [hydroxyurea]) and may be better tolerated.[A214274] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ANAGLYN 0,5 MG SERT KAPSÜL, 100 KAPSÜL ... GRAFTA 0.5 MG SERT KAPSÜL, 100 ADET ... GRELİNE 0.5 MG SERT KAPSÜL, 100 ADET …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 100 ADET ... SULPIVERT 100MG ... SULPIRID-NEURAX 100 MG …

Norethisterone

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone Acetate and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol, and Ferrous Fumarate …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... norethisterone and estrogen ... Genito Urinary System and Sex Hormones …
Matched Products: … PRIMOLUT-N 5 MG TABLET, 1000 ADET …

Scutellaria baicalensis root

Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Scutellariae Radix …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Products: … PALEXIS® RETARD 100 MG ... Nucynta ER Tablets 100 mg ... NUCYNTA ER Tablets 100mg …

Avanafil

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Description: … other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … ANIME® 100 ... SPEDRA TABLET 100MG ... Spedra 100mg Tablets …

Acitretin

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … NEOTIGASON 10 MG KAPSUL, 100 ADET ... NEOTIGASON 25 MG KAPSUL, 100 ADET ... PSÖRETİN 10 MG SERT KAPSÜL ,100 ADET …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. ... [L41790] The intravascular administration of iodine compounds, such as ioversol, enhances the contrast ... (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Iodinated ... Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media …
Matched Products: … Optiray 350 Prefilled Syringe 100ml ... OPTIRAY 240 STERIL ENJEKTABL COZELTI ICEREN CAM SISE, 100 ML ... OPTIRAY 320 STERIL ENJEKTABL COZELTI ICEREN CAM SISE, 100 ML …

Safusidenib

Investigational
Matched Synonyms: … DS-1001 free acid …

Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and ... Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Iodinated ... Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media …
Matched Products: … ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON , 100 ML ... OPAXOL 350 MGl/ML IA/IV ENJEKSİYONLUK ÇÖZELTİ, 100 ML ... INTRATEKAL ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON , 100 ML …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SPIROLON 100 TABLET 100 mg ... CARPIATON 100 ... LETONAL 100 …

Itraconazole

First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Description: … [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … CANDIFORCE-100 Itraconazole Capsules BP 100 mg ... Inox Capsule 100 mg ... MICOTRAZOL® 100 MG …

Histidine

An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn Sulfite Free …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CAREDO Treating Periodontitis Toothpastes 100g …

Hydrocortisone succinate

Approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … A-hydrocort Inj 100mg/2ml ... A-hydrocort Inj 1000mg/8ml ... SOLU-CORTEF INJECTION 100MG (2ML) …

Acarbose

Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal glucoamylase, sucrase, maltase, and isomaltase - which are responsible for the metabolism of complex starches and...
Approved
Investigational
Matched Description: … starches and oligo-, tri-, and disaccharides into absorbable simple sugars. ... the subsequent postprandial increase in blood glucose and insulin levels. ... It inhibits both pancreatic alpha-amylase and membrane-bound alpha-glucosidases - including intestinal …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and acarbose …
Matched Products: … GLUCOBAY 100 TABLET 100 mg ... DITRIUM 100 ... GLUCOBAY 100 …

Capecitabine

Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate …
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acids, Nucleotides, and Nucleosides …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and …
Matched Salts name: … Papaverine sulfate …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … PAPAVERIN HCL BIOFARMA 40 MG / 2ML AMPUL, 100 ADET ... PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 100 ADET ... PAPAVERIN HCL BIOFARMA 60 MG / 2ML AMPUL, 100 ADET …
Displaying drugs 1176 - 1200 of 1544 in total