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Displaying drugs 101 - 125 of 13195 in total
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Synonyms: … 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat ... 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate ... 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester …
Matched Iupac: … 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Salts cas: … 1508-65-2
Matched Products: … MUTUM CR® 10 MG ... LYRINELTABLETAS DE 10 MG ... DITRO 10 MG TABLETAS DE LIBERACION CONTROLADA …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … -thiazole-5-carboxamide ... N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 …
Matched Iupac: … -thiazole-5-carboxamide ... N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 …
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Salts cas: … 35604-67-2
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Synonyms: … 2-phenoxyethanol ... 1-Hydroxy-2-phenoxyethane ... 2-Phenoxyethyl alcohol …
Matched Iupac: … 2-phenoxyethan-1-ol …
Matched Mixtures name: … FITO INTERTULLE, 5 ADET ... FITO INTERTULLE, 10 ADET ... Linola sept 1 mg/g + 10 mg/g Wund-Gel …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid ... 5-(2,4-difluorophenyl)salicylic acid ... 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 10 TABLET ... DOLPHIN 500 MG FILM TABLET, 10 TABLET …
Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Synonyms: … 2-Hydroxyethyl cellulose ether …
Matched Iupac: … 1-{[3,4,5-tris(2-hydroxypropoxy)-6-{[4,5,6-tris(2-hydroxypropoxy)-2-[(2-hydroxypropoxy)methyl]oxan-3- ... yl]oxy}oxan-2-yl]methoxy}propan-2-ol …
Matched Salts name: … Hydroxyethyl cellulose (140 MPa.s at 5%) ... Hydroxyethyl cellulose (280 MPa.s at 5%) ... Hydroxyethyl cellulose (100 MPa.s at 2%) ... Hydroxyethyl cellulose (1800 MPa.s at 2%) ... Hydroxyethyl cellulose (280 MPa.s at 2%) …
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (±)-6-chloro-α-methylcarbazole-2-acetic acid ... (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Description: … Carprofen was previously used in human medicine for over 10 years (1985-1995). …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine ... (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino ... }phenyl)prop-2-enamide …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino ... }phenyl)prop-2-enamide …
Matched Description: … Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid ... 2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Mixtures name: … MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 G …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … MAJEZIK %5 TOPIKAL JEL, 30 G ... MAJEZIK %5 TOPIKAL JEL, 50 G ... MAJEZIK % 5 TOPIKAL SPREY, ÇÖZELTİ, 50 ML …
Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro ... D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)- …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2
Matched Categories: … Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Synonyms: … N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide …
Matched Iupac: … N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide …
Matched Description: … inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … INLYTA (TABLETS 5 MG) ... Axitinib STADA 5 mg Filmtabletten ... Axitinib Sandoz 5 mg – Filmtabletten …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[6-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl]-N-methylaniline …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid …
Matched Iupac: … ]-2-carboxylic acid ... 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl …
Matched Mixtures name: … ทวินสตา 40/10 มก. ... ทวินสตา 80/10 มก. ... CARDIOCAP® A80/10
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … (R)-Carnitine ... 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Mixtures name: … Q 10 Suprabio +L-Carnitine …
Matched Products: … TEFECTUS 2 G/10 ML ORAL ÇÖZELTİ, 10 ADET ... T-KARNIT 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTIN 2 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON ,10 FLAKON …
Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Synonyms: … (-)-cis-5,6,7,8-Tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol …
Matched Iupac: … (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol …
Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Synonyms: … 5,7-dichloro-2-methyl-8-quinolinol ... 2-methyl-5,7-dichloro-8-hydroxyquinoline ... 5,7-dichloro-2-methyl-8-hydroxyquinoline …
Matched Iupac: … 5,7-dichloro-2-methylquinolin-8-ol …
Matched Mixtures name: … IMPETEX %0.1 + %1 KREM, 10 G ... NERISONA-C %0,1 + %1 KREM, 10 GR …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Synonyms: … (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …
Matched Mixtures name: … Qtern 5 mg/10 mg Film-Coated Tablets ... QTERN 5 MG/10 MG FİLM KAPLI TABLET, 28 ADET ... QTERN 5 MG/10 MG FİLM KAPLI TABLET, 84 ADET …
Matched Products: … Onglyza Tablets 5 mg ... อองไกลซา (ชนิดเม็ด 5 มก.) ... ONGLYZA® 5 MG TABLETAS RECUBIERTAS. …
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Synonyms: … (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Mixtures name: … Robaxisal C 1/2 ... Methoxisal-C 1/2
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Description: … event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular events ... cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 ... equally effective from a clinical standpoint, rosuvastatin is considered the most potent; doses of 10
Matched Salts cas: … 147098-20-2
Matched Mixtures name: … ROSALIN 10/5 MG TABLET, 84 ADET ... Rosamib 5 mg/10 mg Tabletten ... ROSALIN 10/5 MG TABLET, 28 ADET …
Matched Products: … KALINEX (R) TABLETASRECUBIERTASX 10 MG ... โอทากิล 5 ... ROVARIL 5 MG …
Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Synonyms: … 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile …
Matched Iupac: … 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile …
Matched Description: … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. …
Matched Products: … MILRINONA 10 MG/10 ML ... MILRINONA 10 MG/ 10 ML ... MILROX 10 MG / 10 ML SOLUCION INYECTABLE …
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Synonyms: … 1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine ... 2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine ... N-Isopropyl-α-(2-methylhydrazino)-p-toluamide …
Matched Iupac: … 4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (R)-2-acetylamino-3-mercaptopropanoic acid ... (R)-mercapturic acid ... (2R)-2-acetylamino-3-sulfanylpropanoic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Mixtures name: … AMINOPLASMAL-5% E INFUSION ... MUCOFIX 600/200 MG EFERVESAN, 5 ADET ... MUCOFIX 900/400 MG EFERVESAN TABLET, 5 ADET …
Matched Products: … FLEMEX(R) - AC OD 600 MG EFFERVESCENT ... FLUIMUCIL® 2% ... HYSTIN SOLUCIONORAL 2 % …
Displaying drugs 101 - 125 of 13195 in total