Displaying drugs 101 - 125 of 2320 in total
Ublituximab
CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.[A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bound cells through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), mediated by...
Approved
Investigational
Matched Description: … one-hour infusion twice-a-year following the starting dose. ... a unique epitope and enhance ADCC compared to other approved anti-CD20 antibodies such as [rituximab ... first and only anti-CD20 monoclonal antibody for multiple sclerosis allowing for administration in a …
Sodium cellulose phosphate
Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... antigens of *Streptococcus pneumoniae* serotype 11A individually conjugated to the CRM197 protein, a …
Fructose
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Recombinant Cholera Toxin B Subunit
Recombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ferumoxides
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Albumin Aggregated
Albumin aggregated is an ingredient in the DRAXIMAGE MAA kit for the preparation of technetium tc99m albumin aggregated injection. This imaging agent is used to assess lung perfusion and for the evaluation of peritoneovenous (LeVeen) shunt patency.
Approved
Lifileucel
Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived T cells from the patient which undergo isolation, ex vivo expansion, and activation Lifileucel was granted accelerated approval by the FDA on February 16, 2024, for the treatment of unresectable or metastatic melanoma.
Approved
Investigational
Matched Description: … Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived …
Albutrepenonacog alfa
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation ... factor IX (rFIX) with a recombinant human albumin (rAlbumin). …
Ammonia
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a food additive in the anhydrous form and serves as a...
Approved
Matched Description: … It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. ... Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal ... Although ammonia is used as a food additive in the anhydrous form and serves as a starting material in …
Raxibacumab
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved
Matched Description: … Raxibacumab has a molecular weight of approximately 146 kilodaltons. ... Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. ... Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of …
Iron isomaltoside 1000
Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others.
Approved
Investigational
Neon
Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. It displays a reddish-orange light,...
Approved
Investigational
Matched Description: … Neon is a chemical element with a chemical symbol Ne and atomic number 10. ... Neon may be used in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion ... It is a noble gas that is colorless, odorless, inert and monatomic. …
Calcium undecylenate
Approved
Experimental
Azficel-T
Azficel-T is an autologous cellular product composed of fibroblasts indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. Dermal fibroblasts are collected from the post-auricular biopsy tissue and aseptically expanded using standard tissue-culture procedures until sufficient cells for three doses are obtained [FDA Label]....
Approved
Investigational
Matched Description: … Expanded cells are then suspended in a cell medium. ... As a replacement for lost dermal constituents in the aging or skin deformation process, treatment with …
Lonoctocog alfa
Approved
Investigational
Ardeparin
Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight...
Approved
Investigational
Withdrawn
Matched Description: … Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant …
Brolucizumab
Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.
Approved
Investigational
Matched Description: … Brolucizumab, also known as RTH258 or ESBA1008,[A187211] is a monoclonal antibody indicated to treat …
Ambrosia acanthicarpa pollen
Ambrosia acanthicarpa pollen is the pollen of the Ambrosia acanthicarpa plant. Ambrosia acanthicarpa pollen is mainly used in allergenic testing.
Approved
Alglucerase
Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated...
Approved
Investigational
Withdrawn
Displaying drugs 101 - 125 of 2320 in total