Sodium cellulose phosphate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sodium cellulose phosphate
DrugBank Accession Number
DB06776
Background

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. 1

This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.

Type
Small Molecule
Groups
Approved
Synonyms
  • Cellulose dihydrogen phosphate, disodium salt
  • Cellulose disodium phosphate
  • Cellulose sodium phosphate

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action

When it is taken orally, it stays in the intestine and it binds strongly to calcium inhibiting its intestinal absorption. From there, inhibition is caused due to the lower intraluminal calcium levels, which is typically available for absorption.2

TargetActionsOrganism
ACalcium ions
binder
Humans
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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International/Other Brands
Calcibind (Mission Pharma)

Categories

ATC Codes
V03AG01 — Sodium cellulose phosphate
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
E6S1NJ4Y5Q
CAS number
9038-41-9

References

General References
  1. Lake KD, Brown DC: New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. [Article]
  2. WikiDoc: Editor-In-Chief: C. Michael Gibson, M.S., M.D. [Link]
RxNav
342965
ChEMBL
CHEMBL1201457
Wikipedia
Sodium_cellulose_phosphate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Targets

Drugtargets2
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Kind
Small molecule
Organism
Humans
Pharmacological action
Yes
Actions
Binder
References
  1. Lake KD, Brown DC: New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. [Article]

Drug created on September 14, 2010 16:21 / Updated on June 12, 2020 16:52