Sodium cellulose phosphate
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Sodium cellulose phosphate
- DrugBank Accession Number
- DB06776
- Background
Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. 1
This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
- Type
- Small Molecule
- Groups
- Approved
- Synonyms
- Cellulose dihydrogen phosphate, disodium salt
- Cellulose disodium phosphate
- Cellulose sodium phosphate
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
When it is taken orally, it stays in the intestine and it binds strongly to calcium inhibiting its intestinal absorption. From there, inhibition is caused due to the lower intraluminal calcium levels, which is typically available for absorption.2
Target Actions Organism ACalcium ions binderHumans - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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- International/Other Brands
- Calcibind (Mission Pharma)
Categories
- ATC Codes
- V03AG01 — Sodium cellulose phosphate
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- E6S1NJ4Y5Q
- CAS number
- 9038-41-9
References
- General References
- External Links
- 342965
- ChEMBL
- CHEMBL1201457
- Wikipedia
- Sodium_cellulose_phosphate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Targets
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1. DetailsCalcium ions
Yes
Binder
References
- Lake KD, Brown DC: New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. [Article]
Drug created at September 14, 2010 16:21 / Updated at June 12, 2020 16:52