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Displaying drugs 101 - 125 of 8563 in total
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Synonyms: … 4-((1E)-2-(4-(2-(2-(2-((SUP 18(F))FLUOROETHOXY)ETHOXY)ETHOXY)PHENYL)ETH-1-EN-1-YL)-N-METHYLANILINE …
Matched Iupac: … 4-[(E)-2-[4-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)phenyl]ethenyl]-N-methylaniline …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Mixtures name: … LEVMONT 2.5/4 MG CIGNEME TABLET, 90 ADET ... LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 90 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET …
Matched Products: … LUXAT 4 MG CIGNEME TABLETI, 90 ADET ... NOTTA 4 MG CIGNEME TABLETI, 90 ADET ... SINMONT 4 MG CIGNEME TABLETI, 90 ADET …
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … Levodopa-4'-monophosphate …
Matched Iupac: … (2S)-2-amino-3-[3-hydroxy-4-(phosphonooxy)phenyl]propanoic acid …
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate …
Approved
Experimental
Matched Synonyms: … 2-(4-Morpholino)thiobenzothiazole ... 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine …
Matched Iupac: … 2-(morpholin-4-ylsulfanyl)-1,3-benzothiazole …
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Approved
Vet approved
Matched Synonyms: … 5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole ... 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide ... 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide …
Matched Iupac: … 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide …
Matched Products: … GANSOL %4 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Synonyms: … trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine ... 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Matched Iupac: … 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Niacinamide 4% ... Adapalene 0.3% / Benzoyl Peroxide 2.5% / Niacinamide 4% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Niacinamide 4% …
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Synonyms: … Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside …
Matched Iupac: … [(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4- …
Matched Salts cas: … 25507-04-4
Matched Mixtures name: … Clindamycin 1% / Niacinamide 4% ... Clindamycin 1% / Niacinamide 4% ... CLINDAMICINA 600 MG / 4 ML SOLUCIÓN INYECTABLE …
Matched Products: … CLINDAMICINA 600 MG / 4 ML ... CLINDAMICINA 600 MG/4 ML INYECTABLE ... CLINDAMICINA INYECTABLE 600 MG/ 4 ML …
Approved
Experimental
Matched Synonyms: … Butyl 4-hydroxybenzoate …
Matched Iupac: … butyl 4-hydroxybenzoate …
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Synonyms: … (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ... all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid …
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. However, the development of KRAS inhibitors has been challenging due to their high affinity for guanosine triphosphate (GTP) and guanosine diphosphate...
Approved
Investigational
Matched Synonyms: … (3,4-d)pyrimidin-4-yl)-1-(2-fluoroprop2-enoyl)piperazin-2-yl)acetonitrile ... )methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2s)- ... ((2s)-4-(7-(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido …
Matched Iupac: … -d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile ... 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5H,6H,7H,8H-pyrido[3,4 …
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline ... 1-oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline ... 3-hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine …
Atovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.
Approved
Matched Synonyms: … 2-(trans-4-(p-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone …
Matched Iupac: … 2-hydroxy-3-[(1r,4r)-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydronaphthalene-1,4-dione …
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Mixtures name: … Mvc 9+4 Inj ... Pregvit Folic 4 ... Re Ob 90 DHA …
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Synonyms: … 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone …
Matched Iupac: … 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one …
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Synonyms: … (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide ... 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine ... N-(2-(1-(3-(isopropylamino)pyridin-2-yl)piperazine-4-carbonyl)-1H-indol-5-yl)methanesulfonamide …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Synonyms: … 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Synonyms: … -7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl …
Matched Iupac: … 7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl- …
Matched Mixtures name: … TAZOJECT 4 G/ 0,5G IV ENJEKSIYONLUK LIYOFILIZE TOZ, 25 ADET ... TAZOJECT 4 G/ 0,5G IV ENJEKSIYONLUK LIYOFILIZE TOZ, (1 ADET FLAKON) ... Piperacillin/Tazobactam Kabi 4 g/0,5 g Pulver zur Herstellung einer Infusionslösung …
Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals. It was approved by the Food and Drug Administration on January 31, 2012 , and by Health Canada in late 2012. Ivacaftor is administered...
Approved
Matched Synonyms: … N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide …
Matched Iupac: … N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide …
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Synonyms: … (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Synonyms: … N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide …
Matched Iupac: … N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide …
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Synonyms: … 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol …
Displaying drugs 101 - 125 of 8563 in total