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Displaying drugs 101 - 125 of 750 in total

Cabazitaxel

Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

Sarocladium strictum

Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG ... BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection …

Guaifenesin

Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and ... continues to be one of very few - if not perhaps the only drug that is readily available and used as …
Matched Mixtures name: … TRIFEN 100 ML SUS. ... Topco tussin cf max ... Core Values Tussin CF …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Topco Mucus Relief ... Up and Up Mucus Relief ... Up and Up Childrens Mucus Relief …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

Panax notoginseng root

Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) ... Notoginseng Root ... San Qi Root …
Matched Name: … Panax notoginseng root …
Matched Description: … Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …

Dendryphiella vinosa

Dendryphiella vinosa is a fungus which can provoke allergic reactions. Dendryphiella vinosa extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Helminthosporium interseminatum …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Acne Vanishing Gel- 10% with Sulfur ... Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit …
Matched Products: … Stubborn Acne Daily Leave-ON Mask ... Daily Leave on Acne Treatment Mask ... Neutrogena Rapid Clear Stubborn Daily Leave On Mask …

AB-201

AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … a HER2-directed CAR and secrete IL-15 ... Ex vivo expanded allogeneic cord blood-derived NK cells that have been genetically modified to express …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …

Mesocricetus auratus skin

Mesocricetus auratus skin or pelt is used in allergenic testing.
Approved
Matched Products: … Hamster Hair and Epithelia …

Cod, unspecified

Cod, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Codfish Gadus callarias …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and …
Matched Mixtures name: … Core Values Tussin CF ... Top Care Flu and Sore Throat ... Comtrex Cough and Cold Day/Night …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... phenylephrine and ketorolac …
Matched Products: … Up and Up nasal decongestant PE ... CareOne Cold and Sinus ... Up and Up Sinus PE …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

TVI-Brain-1

Investigational
Matched Synonyms: … Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination …

Nendratareotide uzatansine

Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …

Phoma exigua var. exigua

Phoma exigua var. exigua is a fungus which can provoke allergic reactions. Phoma exigua var. exigua extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Phoma herbarum …

Lobster

Lobster allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Lobster Homarus americanus …
Displaying drugs 101 - 125 of 750 in total