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Displaying drugs 101 - 125 of 11616 in total

Poliovirus type 2 antigen (formaldehyde inactivated)

Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 2. The vaccine contains purified and inactivated poliovirus type 2 that were...
Approved
Investigational
Matched Description: … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Sucrose

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, ... Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627]. ... of all genotypes of Hepatitis C with or without cirrhosis. …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … important role in protein synthesis and in cell division. ... It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an ... In addition to the above, recent review articles have already demonstrated the important role of zinc …
Matched Mixtures name: … Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea Lozenge ... C & D ... C-plus - Tab …

Indocyanine green acid form

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tixocortol

Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … , in buffer solutions, and in fertilizers and explosives. ... A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia …
Matched Mixtures name: … Zintrexyl-C ... GaviLyte - C TM ... Super C-M-K …

Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Poliovirus type 1 antigen (formaldehyde inactivated)

Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 1. The vaccine contains purified and inactivated poliovirus type 1 that were...
Approved
Investigational
Matched Description: … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Poliovirus type 3 antigen (formaldehyde inactivated)

Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 3. The vaccine contains purified and inactivated poliovirus type 3 that were...
Approved
Investigational
Matched Description: … Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Description: … Barium sulfate occurs in nature as the mineral _barite_. ... This drug is used as a contrast agent in diagnostic x-ray procedures. ... Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Scan C …

Alprazolam

Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.[L34783, L34788] Benzodiazepine treatment should be stopped gradually by tapering down a patient's dose to avoid withdrawal symptoms. Alprazolam's adverse...
Approved
Illicit
Investigational
Matched Products: … Alprazolam C-IV …

Lovastatin

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … has been found to have an average decrease in LDL-C of 25-40%. ... a sequence of metabolic reactions involved in the production of several compounds involved in lipid ... clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin …

Rilonacept

Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in …

N-acetyltyrosine

N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Description: … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …

Nilotinib

Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Description: … benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec), another ... A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic …

Topiramate

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Description: … In 2004, topiramate was approved for the prevention of migraine in adults. ... [A175249] It was initially approved by the FDA in 1996. ... with [phentermine] for chronic weight management therapy in adults. …
Matched Products: … Topamax 15 mg Granulat in Kapseln ... Topamax 25 mg Granulat in Kapseln ... Topamax 50 mg Granulat in Kapseln …

Human interferon beta

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … [L12078] Interferon-beta has been used in the past in clinical studies with other coronaviruses due to ... (MS), and was initially approved by the FDA in 1992. ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in …
Matched Products: … Tetra-C 74% w/w Water Soluble Powder …

Maralixibat

Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Description: … [A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients ... [L38834] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... maralixibat be granted marketing authorization for the treatment of cholestatic pruritus in patients …

Motixafortide

Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … of C-X-C Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow ... [A261476] Motixafortide was approved by the FDA in September 2023, in combination with filgrastim ... , for use in stem cell mobilization prior to autologous stem cell transplant in patients with multiple …

Viltolarsen

Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Description: … Although corticosteroids are effective in slowing disease progression in both DMD and BMD patients, they ... on further verification in confirmatory trials. ... [A218186, L15526] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … a sequence of metabolic reactions involved in the production of several compounds involved in lipid ... clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold ... this class becoming one of the most widely prescribed medications in North America. …
Matched Categories: … Drugs Used in Diabetes …
Displaying drugs 101 - 125 of 11616 in total