Displaying drugs 12651 - 12675 of 12759 in total
Evodenoson
Evodenoson has been used in trials studying the treatment of Open-angle Glaucoma and Ocular Hypertension.
Investigational
Matched Iupac: … }prop-2-yn-1-yl)piperidine-1-carboxylate ... methyl 4-(3-{6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Satavaptan
Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).
Investigational
Matched Iupac: … N-tert-butyl-3-methoxy-4-{[(1s,4s)-5'-ethoxy-4-[2-(morpholin-4-yl)ethoxy]-2'-oxo-1',2'-dihydrospiro[cyclohexane ... -1,3'-indol]-1'-yl]sulfonyl}benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Remogliflozin etabonate
Remogliflozin etabonate has been used in trials studying the treatment and basic science of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … }-1H-pyrazol-3-yl]oxy}oxan-2-yl]methyl carbonate ... ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-{[5-methyl-1-(propan-2-yl)-4-{[4-(propan-2-yloxy)phenyl]methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(C8-R)-hydantocidin 5'-phosphate
Experimental
Matched Iupac: … 2R)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan-3- …
Ceftezole
Experimental
Matched Iupac: … (6R,7R)-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia ... -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Hemoporfin
Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Investigational
Matched Iupac: … 3-[20-(2-carboxyethyl)-10,15-bis(1-hydroxyethyl)-5,9,14,19-tetramethyl-21,22,23,24-tetraazapentacyclo ... [16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-4-yl]propanoic …
Matched Description: … Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Crinecerfont
Investigational
Matched Iupac: … 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N ... -(prop-2-yn-1-yl)-1,3-thiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Freselestat
Experimental
Investigational
Matched Iupac: … -1-hydroxy-3-methylbutan-2-yl]acetamide ... 2-(5-amino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-yl)-N-[(1R,2R)-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(C8-S)-Hydantocidin 5'-phosphate
Experimental
Matched Iupac: … 2S)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan-3- …
Cefalonium
Experimental
Vet approved
Matched Iupac: … oct-2-en-3-yl]methyl}pyridin-1-ium ... 4-carbamoyl-1-{[(6R,7R)-2-carboxylato-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0] …
Filibuvir
Filibuvir has been used in trials studying the treatment of Hepatitis, Hepatitis C, and Chronic Hepatitis C.
Investigational
Matched Iupac: … (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Telcagepant
Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Iupac: … N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-{2-oxo-1H,2H,3H-imidazo ... [4,5-b]pyridin-1-yl}piperidine-1-carboxamide …
Matched Description: … It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cefetamet
Experimental
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo …
TMP
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Firsocostat
Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).
Investigational
Matched Iupac: … ,4H-thieno[2,3-d]pyrimidin-3-yl}-2-methylpropanoic acid ... 2-{1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxo-1H,2H,3H …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
p-Toluenesulfonamide
Investigational
Matched Synonyms: … Tolbutamide impurity a …
Matched Iupac: … 4-methylbenzene-1-sulfonamide …
Matched Iupac: … 4-methylbenzene-1-sulfonamide …
Sagopilone
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Iupac: … -(prop-2-en-1-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione ... (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-1,3-benzothiazol-5-yl)-10 …
Matched Description: … Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism ... It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism ... It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pentamycin
Experimental
Matched Iupac: … (1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one ... (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[ …
Lifirafenib
Lifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Investigational
Matched Iupac: … 5-{[(2R,3R,4S)-3-[6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]-5-oxatricyclo[4.4.0.0^{2,4}]deca-1(6), …
Nikkomycin Z
Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
Investigational
Matched Iupac: … -(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid ... (2S)-2-[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanamido]-2-[(2R,3S,4R,5R)-5 …
Sucrosofate
Experimental
Matched Iupac: … sulfooxy)methyl]-5-{[(2R,3R,4S,5R,6R)-3,4,5-tris(sulfooxy)-6-[(sulfooxy)methyl]oxan-2-yl]oxy}oxolan-3- …
Carbenoxolone
An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [PubChem]
Experimental
Matched Iupac: … (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-[(3-carboxypropanoyl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13 …
Matched Salts cas: … 7421-40-1 …
Matched Salts cas: … 7421-40-1 …
Patupilone
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Iupac: … (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4- ... yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione …
Matched Description: … Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol. …
Matched Description: … Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol. …
Ipatasertib
Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Investigational
Matched Iupac: … -1-yl}-3-[(propan-2-yl)amino]propan-1-one ... (2S)-2-(4-chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl]piperazin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
TNP-2092
TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).
Investigational
Matched Iupac: … 8-[(3R)-3-[1-({1-[(E)-{[(7S,9E,11S,12S,13S,14S,15R,16R,17S,18S,19E)-13-(acetyloxy)-2,15,17,27,29-pentahydroxy ... yl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic acid ... 3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1( ... 2,4,9,19,21,25(29),26-octaen-26-yl]methylidene}amino]piperidin-4-yl}(methyl)amino)cyclopropyl]pyrrolidin-1- …
Displaying drugs 12651 - 12675 of 12759 in total