Cefetamet

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Cefetamet
DrugBank Accession Number
DB13504
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 397.42
Monoisotopic: 397.051460951
Chemical Formula
C14H15N5O5S2
Synonyms
  • Cefetamet
  • Céfétamet
  • Cefetametum
External IDs
  • LY-97964
  • LY097964
  • RO 15-8074

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirCefetamet may decrease the excretion rate of Abacavir which could result in a higher serum level.
AbciximabThe therapeutic efficacy of Abciximab can be decreased when used in combination with Cefetamet.
AceclofenacThe risk or severity of nephrotoxicity can be increased when Aceclofenac is combined with Cefetamet.
AcemetacinThe risk or severity of nephrotoxicity can be increased when Cefetamet is combined with Acemetacin.
AcenocoumarolThe risk or severity of bleeding can be increased when Cefetamet is combined with Acenocoumarol.
Food Interactions
Not Available

Products

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Categories

ATC Codes
J01DD10 — Cefetamet
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as cephalosporins. These are compounds containing a 1,2-thiazine fused to a 2-azetidinone to for a oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid moiety or a derivative thereof.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Lactams
Sub Class
Beta lactams
Direct Parent
Cephalosporins
Alternative Parents
N-acyl-alpha amino acids and derivatives / 2,4-disubstituted thiazoles / 1,3-thiazines / 2-amino-1,3-thiazoles / Tertiary carboxylic acid amides / Heteroaromatic compounds / Secondary carboxylic acid amides / Amino acids / Azetidines / Thiohemiaminal derivatives
show 9 more
Substituents
1,3-thiazol-2-amine / 2,4-disubstituted 1,3-thiazole / Alpha-amino acid or derivatives / Amine / Amino acid / Amino acid or derivatives / Aromatic heteropolycyclic compound / Azacycle / Azetidine / Azole
show 23 more
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
4R5TV783X3
CAS number
65052-63-3
InChI Key
MQLRYUCJDNBWMV-GHXIOONMSA-N
InChI
InChI=1S/C14H15N5O5S2/c1-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24-2)6-4-26-14(15)16-6/h4,8,12H,3H2,1-2H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1
IUPAC Name
(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
SMILES
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O

References

General References
Not Available
KEGG Drug
D03424
ChemSpider
4589562
RxNav
20482
ChEBI
135629
ChEMBL
CHEMBL2103764
ZINC
ZINC000004215237
Wikipedia
Cefetamet

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Syrup
SuspensionOral
Tablet
Tablet250 MG
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.174 mg/mLALOGPS
logP-0.18ALOGPS
logP-0.65Chemaxon
logS-3.4ALOGPS
pKa (Strongest Acidic)2.72Chemaxon
pKa (Strongest Basic)3.61Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count8Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area147.21 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity94.18 m3·mol-1Chemaxon
Polarizability37.42 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0002-0219000000-f93e760a80a57d23fec7
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-000i-2293000000-59120531cf87919ac37b
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0w29-0779000000-91c60df1a38fe2366257
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-01c0-2739000000-1c9bcfc4053c4bcdd1ad
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0ik9-0967000000-66ddefec5f1cd88e0d4c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-00fr-1900000000-6b3cd1b51771db393b83
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-190.1504319
predicted
DarkChem Lite v0.1.0
[M-H]-184.54036
predicted
DeepCCS 1.0 (2019)
[M+H]+189.4641319
predicted
DarkChem Lite v0.1.0
[M+H]+186.93593
predicted
DeepCCS 1.0 (2019)
[M+Na]+190.2191319
predicted
DarkChem Lite v0.1.0
[M+Na]+192.84846
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:43 / Updated at February 21, 2021 18:54