Displaying drugs 1251 - 1275 of 1440 in total
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Synonyms: … Recombinant human TNF …
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and ... (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and ... (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Thyrotropin alfa
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Synonyms: … Recombinant Human Thyroid Stimulating Hormone …
Matched Description: … chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). ... linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and ... alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). ... linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and ... alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Anterior Pituitary Lobe Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Crefmirlimab
Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Investigational
Matched Synonyms: … Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells) …
Matched Description: … Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers …
Matched Description: … Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers …
NZ-1002
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
N-acetyl-beta-D-galactosamine 6-sulfate
Experimental
Matched Synonyms: … 2-(acetylamino)-2-deoxy-6-O-sulfo-β-D-galactopyranose …
Zamerovimab
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 1a9 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma …
Tobevibart
Tobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).
Investigational
Matched Synonyms: … Immunoglobulin G1 [238-alanine,332-leucine,334-glutamic acid,430-leucine,436-serine], anti-(hepatitis ... B virus surface antigen) (human monoclonal VIR-3434 γ1-chain), disulfide with human monoclonal VIR-3434 …
Tipapkinogene sovacivec
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus strain MVA human papillomavirus-targeted) …
Vitespen
Investigational
Matched Synonyms: … Endoplasmin (human tumor rejection antigen 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Priliximab
Investigational
Matched Synonyms: … Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
INZ-701
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
Matched Synonyms: … Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and …
Matched Description: … intention to be used for the treatment of calcification disorders of the circulatory system, bones, and …
PRX-ASL
PRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Investigational
Matched Synonyms: … Modified messenger ribonucleic acid encoding human argininosuccinate lyase enzyme encapsulated into lipid …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT ... PROTEIN WITH HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT (232 C-TERMINAL RESIDUES) (66-297) (HOMO SAPIENS IGHG1 ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mazorelvimab
Investigational
Matched Synonyms: … .1-chain), disulfide with human-mus musculus clone 2g11 .kappa. ... Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Human brain natriuretic factor-32 …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AGT-182
AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
Investigational
Matched Synonyms: … Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase …
Matched Description: … investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and ... a human insulin receptor monoclonal antibody. …
Matched Description: … investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and ... a human insulin receptor monoclonal antibody. …
L-cysteic acid
L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.
Experimental
Matched Synonyms: … 3-sulfo-L-alanine …
Matched Description: … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather ... It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Compounds ... Amino Acids, Sulfur …
Matched Description: … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather ... It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Compounds ... Amino Acids, Sulfur …
Recifercept
Investigational
Matched Synonyms: … Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble ... Recombinant human fibroblast growth factor receptor 3 ... isoform (337-400>del, 414-784>del)-sfgfr3), produced in chinese hamster ovary (cho) cells, glycoform …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... and maintenance of hemostasis [A18581]. ... in increased mechanical strength and resistance to fibrinolysis of the fibrin clot. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... and maintenance of hemostasis [A18581]. ... in increased mechanical strength and resistance to fibrinolysis of the fibrin clot. …
Matched Categories: … Blood and Blood Forming Organs …
Basic Fibroblast Growth Factor
Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative...
Investigational
Matched Synonyms: … Basic fibroblast growth factor, recombinant human, KCB-1 ... Recombinant human basic fibroblast growth factor, KCB-1 …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
S-sulphocysteine
Experimental
Matched Synonyms: … S-sulfo-L-cysteine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Compounds ... Amino Acids, Sulfur …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sulfur Compounds ... Amino Acids, Sulfur …
Cipaglucosidase alfa
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... MONOCLONAL OMS721 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL OMS721 .LAMBDA. ... MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS …
Chondrus crispus
Chondrus crispus is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Chondrus Crispus Whole …
Displaying drugs 1251 - 1275 of 1440 in total