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Displaying drugs 1276 - 1300 of 1963 in total
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores ... of lead from the body. …
Matched Categories: … Diet, Food, and Nutrition ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … Calcium Edetate de Sodium
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE ... IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE …
Matched Description: … [L48041] While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Lonicera confusa flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Gold-silver Flower (Lonicera Confusa) …
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), ... disulfide with human monoclonal CSL312 lambda-chain, dimer …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and ... Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy …
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Synonyms: … liso-cel
Matched Description: … autoleucel] and [axicabtagene ciloleucel]. ... [A228493] Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval ... [L31588] CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... CD19-Directed Genetically Modified Autologous T-cell Immunotherapies …
Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.
Approved
Matched Products: … Vivotif 2 x 10^9 - 2 x 10^10 CFU magensaftresistente Hartkapsel …
Investigational
Matched Synonyms: … anti-CD5 CAR T cells
Matched Name: … Anti-CD5 CAR T-cell therapy …
Red blood cell-encapsulated L-asparaginase is Asparaginase Escherichia coli encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. It is being investigated in cancers.
Investigational
Matched Synonyms: … L-asparaginase encapsulated in red blood cells
Matched Name: … Red blood cell-encapsulated L-asparaginase …
Matched Description: … red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. ... Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived …
Matched Categories: … Enzymes and Coenzymes …
Investigational
Matched Synonyms: … Recombinant human endostatin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide ... with human monoclonal m281 .lambda. …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4(228-proline), anti-(human cd47 antigen) (human monoclonal tj011133 .gamma.4-chain), ... disulfide with human monoclonal tj011133 .kappa. …
Matched Description: … Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and ... Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and ... Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax …
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human
Investigational
Matched Synonyms: … Human coxsackievirus A21 ... Enterovirus human enterovirus C serogroup coxsackievirus serotype A21 …
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Human monoclonal antibody based on an IgG1 lambda framework against human interferon gamma …
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational
Matched Synonyms: … Human hemoglobin …
Matched Description: … The respiratory protein of the red blood cells. It consists primarily of globin and heme. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Human fibrin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human epidermal growth factor receptor her3) (human monoclonal isu104 .gamma ... .1-chain), disulfide with human monoclonal isu104 .lambda. …
Investigational
Matched Synonyms: … Allogeneic ex vivo expanded umbilical cord blood cells
Investigational
Matched Synonyms: … Allogeneic gene edited BCMA-directed CAR T cells
Trichosporon cutaneum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Trichosporon cutaneum whole
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza A virus A/South Australia/55/2014 (H3N2) whole
Matched Description: … ) and of cell-mediated immunity through the production of T-lymphocytes. ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated …
Investigational
Matched Synonyms: … Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3 ... chimeric antigen receptor (CAR) modified recombinant T cells targeting B7-H3 ... allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR) …
Matched Name: … B7-H3-specific chimeric antigen receptor T cells
Investigational
Matched Synonyms: … (3r)-1-azabicyclo(2.2.2)octan-3-yl (3-fluorophenyl)((3,4,5-trifluorophenyl)methyl)carbamate
Displaying drugs 1276 - 1300 of 1963 in total