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Displaying drugs 13051 - 13075 of 13918 in total
An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … (2R)-2-Hydroxy-3-(phosphonooxy)-propanal ... Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Iupac: … [(2R)-2-hydroxy-3-oxopropoxy]phosphonic acid …
Experimental
Matched Iupac: … (2R)-2-amino-3-(sulfosulfanyl)propanoic acid …
Investigational
Matched Synonyms: … 2-amino-9-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-6-mercaptopurine ... 2'-deoxy-6-thioguanosine ... 2'-desoxy-6-thioguanosine …
Matched Name: … 2'-deoxythioguanosine …
Matched Iupac: … 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purine-6-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Name: … (2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(2-sulfanylethyl)piperazine-2-carboxamide …
Experimental
Matched Name: … (2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(3-sulfanylpropyl)piperazine-2-carboxamide …
A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Experimental
Matched Synonyms: … L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide …
Matched Iupac: … (4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo …
Matched Description: … at positions 2 and 5, which form the heterocycle via a disulfide bond. ... A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located …
Elamipretide has been used in trials studying the treatment of Leber's Hereditary Optic Neuropathy.
Investigational
Matched Iupac: … ]-N-[(1S)-1-carbamoyl-2-phenylethyl]hexanamide ... (2S)-6-amino-2-[(2S)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-3-(4-hydroxy-2,6-dimethylphenyl)propanamido …
Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17. Davunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in...
Investigational
Matched Iupac: … (2S)-2-{[(2S)-1-[(2S,3S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanoyl ... ]pyrrolidin-2-yl]formamido}-3-methylbutanamido]-3-hydroxypropanamido]-3-methylpentanoyl]pyrrolidin-2- …
Matched Description: … Davunetide is derived from a naturally occurring neuroprotective brain protein known as activity dependent …
PM02734 is a marine derived compound. PM02734 as a new antiproliferative drug demonstrating activity against a broad spectrum of tumor types: breast, colon, pancreas, lung and prostate, among others.
Investigational
Matched Description: … PM02734 is a marine derived compound. ... PM02734 as a new antiproliferative drug demonstrating activity against a broad spectrum of tumor types …
G305 is a recombinant NY-ESO-1 protein plus glucopyranosyl lipid A (GLA) in a stable emulsion (SE). G305 is an active component of CMB305 along with LV305.
Investigational
Matched Description: … G305 is a [recombinant NY-ESO-1 protein] plus glucopyranosyl lipid A (GLA) in a stable emulsion (SE). …
Experimental
Matched Name: … 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine …
Matched Iupac: … 9-butyl-8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine …
S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746.
Investigational
Matched Description: … S65487 a potent and selective BCL-2 inhibitor, and a prodrug of S55746. …
Experimental
Matched Name: … 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide …
Matched Iupac: … 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide …
A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy …
Matched Description: … A tryptophan hydroxylase inhibitor. ... [Telotristat ethyl] (brand name Xermelo) is a prodrug of telotristat. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3'-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. This medication targets the protein purine nucleoside phosphorylase.
Experimental
Matched Name: … 3'-deoxyguanosine …
Matched Iupac: … 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … 3'-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. ... These are compounds comprising a purine base attached to a sugar. …
A natural product that has been considered as a growth factor for some insects. [PubChem]
Experimental
Matched Iupac: … 2-amino-6-[(1S,2R)-1,2-dihydroxypropyl]-3,4-dihydropteridin-4-one …
Matched Description: … A natural product that has been considered as a growth factor for some insects. [PubChem] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Name: … N-{[(2S,3S)-3-(Ethoxycarbonyl)-2-oxiranyl]carbonyl}-L-threonyl-L-isoleucine …
Matched Iupac: … (2S,3S)-2-[(2S,3R)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-hydroxybutanamido]-3-methylpentanoic …
Experimental
Matched Synonyms: … 3-(oxidosulfanyl)-L-alanine …
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid …
Experimental
Experimental
Matched Name: … N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE …
Matched Iupac: … 4-{[2-(3-benzenesulfonamido-5-methylphenoxy)ethyl]amino}pyridin-1-ium …
Thymectacin, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, is a novel small molecule anticancer agent. Thymectacin is selectively active against tumor cells expressing high levels of thymidylate synthase (TS), a critical enzyme in DNA biosynthesis. Thymectacin was as efficacious as irinotecan, a drug recently approved for the treatment of 5-fluorouracil-resistant colon cancer.
Investigational
Matched Iupac: … methyl (2S)-2-[({[(2R,3S,5R)-5-{5-[(E)-2-bromoethenyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}-3- ... hydroxyoxolan-2-yl]methoxy}(phenoxy)phosphoryl)amino]propanoate …
Matched Description: … Thymectacin, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, is a novel small molecule ... Thymectacin is selectively active against tumor cells expressing high levels of thymidylate synthase (TS), a ... Thymectacin was as efficacious as irinotecan, a drug recently approved for the treatment of 5-fluorouracil-resistant …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.
Investigational
Matched Description: … a topoisomerase I inhibitor. ... Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to …
Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It presents a unique chemical structure that does not follow the structural properties of other drugs of its class. Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. However, it...
Experimental
Matched Synonyms: … 2-Phenyl-4-(2-(4-piperidyl)ethyl)quinoline …
Matched Iupac: … 2-phenyl-4-[2-(piperidin-4-yl)ethyl]quinoline …
Matched Description: … However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic ... Due to these differences, this drug is classified as a nonbenzodiazepine anxiolytic. ... Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 13051 - 13075 of 13918 in total