Displaying drugs 13101 - 13125 of 13918 in total
Empegfilgrastim
Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational
Listeria monocytogenes
Investigational
CDX-6210
CDX-6210 is a modified version of a leucine decarboxylase enzyme from Planctomycetaceae bacterium.
Investigational
Matched Description: … CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_. …
BVX-001
BVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
Investigational
Matched Description: … BVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate. …
3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE
Experimental
Matched Name: … 3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE …
Matched Iupac: … 3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …
Matched Iupac: … 3-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide …
PLX8394
PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors).
Investigational
Matched Iupac: … (3R)-N-{3-[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}- ... 3-fluoropyrrolidine-1-sulfonamide …
Matched Description: … PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in …
Matched Description: … PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in …
Ribaxamase
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Description: … of c.diff in Patients With a LRTI). ... Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention …
Carbomer
Experimental
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …
Matched Description: … It acts as a p38 MAP kinase inhibitor. ... VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases ... In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy …
Matched Description: … It acts as a p38 MAP kinase inhibitor. ... VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases ... In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy …
Uridine-5'-Diphosphate
A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem]
Experimental
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem] …
Matched Description: … A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem] …
Cytochrome C
Cytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain.
Investigational
Matched Description: … Cytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain. …
RGX-202
RGX-202 is a recombinant AAV8 that contains a vector genome encoding a miniaturized dystrophin protein (microdystrophin).
Investigational
Matched Description: … RGX-202 is a recombinant AAV8 that contains a vector genome encoding a miniaturized dystrophin protein …
(2R,4S)-2-[(R)-BENZYLCARBAMOYL-PHENYLACETYL-METHYL]-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID
Experimental
Matched Name: … (2R,4S)-2-[(R)-BENZYLCARBAMOYL-PHENYLACETYL-METHYL]-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID …
Matched Iupac: … (2R,4S)-2-[(R)-(benzylcarbamoyl)(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic …
Matched Iupac: … (2R,4S)-2-[(R)-(benzylcarbamoyl)(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE …
Matched Iupac: … (2S,3S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic …
Matched Iupac: … (2S,3S)-2-[(2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic …
N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE
Experimental
Matched Name: … N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE …
Matched Iupac: … (2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxiran-2-yl]formamido}-3-methylpentanoyl]pyrrolidine-2 …
Matched Iupac: … (2S)-1-[(2S,3S)-2-{[(2S,3S)-3-(benzylcarbamoyl)oxiran-2-yl]formamido}-3-methylpentanoyl]pyrrolidine-2 …
PF-05180999
PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability of a Modified-Release Formulation of PF-05180999).
Investigational
Matched Iupac: … 2-{4-[4-(azetidin-1-yl)-7-methylimidazo[4,3-f][1,2,4]triazin-5-yl]-1-methyl-1H-pyrazol-5-yl}-5-(trifluoromethyl …
Matched Description: … of a Modified-Release Formulation of PF-05180999). ... PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability …
Matched Description: … of a Modified-Release Formulation of PF-05180999). ... PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability …
Emerfetamab
Emerfetamab is a bispecific T cell engager antibody construct with a half-life extension Fc moiety capable of binding to the neonatal Fc receptor.
Investigational
Matched Description: … Emerfetamab is a bispecific T cell engager antibody construct with a half-life extension Fc moiety capable …
methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate
Experimental
Matched Name: … methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate …
Matched Iupac: … methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate …
Matched Iupac: … methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate …
MTL-CEBPA
MTL-CEBPA is a SMARTICLES liposomal formulation of MTL-501, a small activating RNA (saRNA) oligonucleotide.
Investigational
Matched Description: … MTL-CEBPA is a SMARTICLES liposomal formulation of MTL-501, a small activating RNA (saRNA) oligonucleotide …
Cyclic GMP
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … 3',5'-cyclic GMP ... Guanosine 3',5'-cyclic phosphate ... Guanosine 3',5'-cyclic monophosphate …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. ... Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. ... Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Wortmannin
Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Experimental
Matched Iupac: … 10),12(19),14-trien-3-yl acetate ... methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0^{2,10}.0^{5,9}.0^{15,19}]nonadeca-2( …
Matched Description: … This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). ... Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. …
Matched Description: … This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). ... Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. …
Imidazole salicylate
Experimental
Matched Synonyms: … Imidazole-2-hydroxybenzoate …
Matched Iupac: … 1H-imidazole; 2-hydroxybenzoic acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1H-imidazole; 2-hydroxybenzoic acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring …
Vincamine
Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Experimental
Matched Description: … Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Caroxazone
Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Withdrawn
Matched Iupac: … 2-(2-oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide …
Matched Description: … It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. ... However, it presents a five-fold preference for the MAO-B subtype. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. ... However, it presents a five-fold preference for the MAO-B subtype. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 13101 - 13125 of 13918 in total