Displaying drugs 13126 - 13150 of 13918 in total
Sepofarsen
Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)).
Investigational
Matched Description: … , Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)). ... Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety …
8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
Experimental
Matched Name: … 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-9-(pent-4-yn-1-yl)-9H-purin-6-amine …
Matched Iupac: … 8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-9-(pent-4-yn-1-yl)-9H-purin-6-amine …
6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE
Experimental
Matched Name: … 6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE …
Matched Iupac: … 6-ethyl-5-[9-(3-methoxypropyl)-9H-carbazol-2-yl]pyrimidine-2,4-diamine …
Matched Iupac: … 6-ethyl-5-[9-(3-methoxypropyl)-9H-carbazol-2-yl]pyrimidine-2,4-diamine …
Human umbilical cord blood mononuclear cell-conditioned medium
Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines these cells secrete are also implicated. When HUCBCs secrete growth factors and anti-inflammatory cytokines, they are...
Investigational
Merbromin
Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market due to the possibility...
Experimental
Matched Iupac: … disodium [2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3H-xanthen-5-yl]mercurol …
Matched Description: … Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. ... It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Description: … Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. ... It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Tetrahydrocannabivarin
Tetrahydrocannabivarin (THCV) is a propyl analogue of tetrahydrocannabinol (Δ9-THC), one of the primary pharmacological components of Medical Cannabis. Δ9-THC is currently available in several synthetic forms, including Dronabinol, while purified or isolated THCV is not approved for any medical uses and is not available as any marketed products. As a...
Investigational
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-propyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a partial agonist of CB2 [A32477]. ... and 2 (CB1 and CB2)[A32585]. ... largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 …
Matched Description: … (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a partial agonist of CB2 [A32477]. ... and 2 (CB1 and CB2)[A32585]. ... largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 …
METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE
Experimental
Matched Name: … METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE …
Matched Iupac: … (2R)-4-{[(2R)-4-methoxy-4-oxobutan-2-yl]oxy}-4-oxobutan-2-yl (3R)-3-hydroxybutanoate …
Matched Iupac: … (2R)-4-{[(2R)-4-methoxy-4-oxobutan-2-yl]oxy}-4-oxobutan-2-yl (3R)-3-hydroxybutanoate …
N-[2-(2,4-diaminopyrido[2,3-d]pyrimidin-7-yl)-2-methylpropyl]-4-phenoxybenzamide
Experimental
Matched Name: … N-[2-(2,4-diaminopyrido[2,3-d]pyrimidin-7-yl)-2-methylpropyl]-4-phenoxybenzamide …
Matched Iupac: … N-(2-{2,4-diaminopyrido[2,3-d]pyrimidin-7-yl}-2-methylpropyl)-4-phenoxybenzamide …
Matched Iupac: … N-(2-{2,4-diaminopyrido[2,3-d]pyrimidin-7-yl}-2-methylpropyl)-4-phenoxybenzamide …
Peptide YY (3-36)
Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Investigational
Matched Synonyms: … PYY 3-36 ... PYY(3-36) ... Pyy (3-36) peptide …
Matched Name: … Peptide YY (3-36) …
Matched Description: … Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
Matched Name: … Peptide YY (3-36) …
Matched Description: … Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
Uridine diphosphate glucose
A key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid. Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy ... ({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
Matched Description: … A key intermediate in carbohydrate metabolism. ... Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids. ... Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … A key intermediate in carbohydrate metabolism. ... Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids. ... Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lancovutide
Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is closely related to cinnamycin (Ro09-0198). It belongs to the lantibiotics. Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of...
Investigational
Matched Iupac: … trithia-3,6,9,15,18,21,24,27,30,33,36,39,46,49,52,55,58,60,66-nonadecaazapentacyclo[38.18.9.3^{19,56}.3^ ... 25S,28R,31S,37S,40S,41S,44R,47S,50S,53S,56R,65S,70S)-44-amino-47-(4-aminobutyl)-4,16,22-tribenzyl-50-(2- ... hydroxy)methyl]-41,70-dimethyl-2,5,8,14,17,20,23,26,29,32,35,38,45,48,51,54,57,67-octadecaoxo-25-(propan-2- …
Matched Description: … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. ... Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is ... Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of unusual …
Matched Description: … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. ... Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is ... Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of unusual …
LU-31130
LU-31130 is a rapid acting therapy developed by H. Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. It acts at the Dopamine D4 receptors in the cortex and has low affinity for D2 receptors, adrenoceptors, muscarinic and histaminergic receptors.
It provides anti-psychotic characteristic and a low incidence of extrapyramidal...
Investigational
Matched Description: … LU-31130 is a rapid acting therapy developed by H. ... Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. ... It provides anti-psychotic characteristic and a low incidence of extrapyramidal and cardiovascular side …
Virginiamycin
Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination and in livestock to prevent and treat infections. According to a USDA study, antibiotics can save as much...
Vet approved
Matched Iupac: … [23.2.1.0^{3,7}]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone; N-[(3S,6S,12R,15S,16R,19S ... [20.4.0.0^{6,10}]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide ... (10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-(propan-2-yl)-9,26-dioxa-3,15,28-triazatricyclo ... ,22S)-3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentaazatricyclo …
Matched Description: … It is a combination of pristinamycin IIA and virginiamycin S1. ... Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. ... According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. …
Matched Description: … It is a combination of pristinamycin IIA and virginiamycin S1. ... Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. ... According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. …
SB-559448
SB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets. This drug is developed by GlaxoSmithKline and used to treat Thrombocytopenia.Thrombocytopenia (decreased platelet count) is a common side effect of many chemotherapies and can lead to uncontrolled...
Investigational
Matched Description: … SB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor ... common side effect of many chemotherapies and can lead to uncontrolled bleeding, thus representing a ... by GlaxoSmithKline and used to treat Thrombocytopenia.Thrombocytopenia (decreased platelet count) is a …
Resiniferatoxin
Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain).
Investigational
Matched Iupac: … [11.4.1.0^{1,10}.0^{2,6}.0^{11,15}]octadeca-3,8-dien-8-yl]methyl 2-(4-hydroxy-3-methoxyphenyl)acetate ... [(1R,2R,6R,10S,11R,15R,17R)-13-benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo …
Matched Description: … Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid ... receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission …
Matched Description: … Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid ... receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission …
Diclazuril
Diclazuril is a coccidiostat.
Investigational
Vet approved
Matched Iupac: … 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-2-yl)phenyl]acetonitrile …
Matched Description: … Diclazuril is a coccidiostat. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Diclazuril is a coccidiostat. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tanaproget
Tanaproget (NSP-989) is an investigational non-steroidal progestin. It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins. Because of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the...
Investigational
Matched Iupac: … 5-(4,4-dimethyl-2-sulfanylidene-2,4-dihydro-1H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile …
Matched Description: … It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective ... An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging ... It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective ... An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging ... It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
XEN-2174
XEN-2174 is a synthetic drug modeled on a peptide from the venom of a cone shell found on Australia's Great Barrier Reef. XEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the Norepinephrine Transporter (NET). NET is the primary mechanism regulating the biological effects of...
Investigational
Matched Description: … XEN-2174 is a synthetic drug modeled on a peptide from the venom of a cone shell found on Australia's ... XEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the …
Betacetylmethadol
A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
Experimental
Illicit
Matched Iupac: … (3S,6R)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … A narcotic analgesic with a long onset and duration of action. …
Matched Description: … A narcotic analgesic with a long onset and duration of action. …
Mongersen
Mongersen is under investigation in clinical trial NCT02957474 (A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects).
Investigational
Matched Description: … Mongersen is under investigation in clinical trial NCT02957474 (A Study to Evaluate the Effect of Food ... , Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects …
Lanoteplase
Investigational
Sulfotep
Experimental
Vet approved
Englitazone
Englitazone is a hypoglycemic agent.
Experimental
Matched Iupac: … 5-{[(2R)-2-benzyl-3,4-dihydro-2H-1-benzopyran-6-yl]methyl}-1,3-thiazolidine-2,4-dione …
Matched Description: … Englitazone is a hypoglycemic agent. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Englitazone is a hypoglycemic agent. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
MT-0169
MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.
Investigational
Matched Description: … a human single chain variable fragment with affinity for human CD38 cell surface protein. ... MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to …
(3R,4R,5S,6R)-6-Fluoro-3,4,5-trihydroxytetrahydro-2H-pyran-2-olate
Experimental
Matched Name: … (3R,4R,5S,6R)-6-Fluoro-3,4,5-trihydroxytetrahydro-2H-pyran-2-olate …
Matched Iupac: … (3R,4R,5S,6R)-6-fluoro-3,4,5-trihydroxyoxan-2-olate …
Matched Iupac: … (3R,4R,5S,6R)-6-fluoro-3,4,5-trihydroxyoxan-2-olate …
Displaying drugs 13126 - 13150 of 13918 in total