Displaying drugs 13151 - 13175 of 13944 in total
N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE
Experimental
Matched Name: … N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE …
Matched Iupac: … 5-chloro-N'-[2-(trifluoromethyl)benzenesulfonyl]-1-benzofuran-2-carbohydrazide …
Matched Iupac: … 5-chloro-N'-[2-(trifluoromethyl)benzenesulfonyl]-1-benzofuran-2-carbohydrazide …
PLX8394
PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors).
Investigational
Matched Iupac: … (3R)-N-{3-[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}- ... 3-fluoropyrrolidine-1-sulfonamide …
Matched Description: … PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in …
Matched Description: … PLX8394 is under investigation in clinical trial NCT02428712 (A Study of PLX8394 as a Single Agent in …
Ribaxamase
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Description: … of c.diff in Patients With a LRTI). ... Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention …
Tetrahydrocannabivarin
Tetrahydrocannabivarin (THCV) is a propyl analogue of tetrahydrocannabinol (Δ9-THC), one of the primary pharmacological components of Medical Cannabis. Δ9-THC is currently available in several synthetic forms, including Dronabinol, while purified or isolated THCV is not approved for any medical uses and is not available as any marketed products. As a...
Investigational
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-propyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a partial agonist of CB2 [A32477]. ... and 2 (CB1 and CB2)[A32585]. ... largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 …
Matched Description: … (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a partial agonist of CB2 [A32477]. ... and 2 (CB1 and CB2)[A32585]. ... largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 …
Danegaptide
Danegaptide has been investigated for the treatment of Focus of Study is STEMI.
Investigational
Matched Iupac: … (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid …
Vafidemstat
Vafidemstat is under investigation in clinical trial NCT03867253 (Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease).
Investigational
Matched Iupac: … 5-({[(1R,2S)-2-[4-(benzyloxy)phenyl]cyclopropyl]amino}methyl)-1,3,4-oxadiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-05180999
PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability of a Modified-Release Formulation of PF-05180999).
Investigational
Matched Iupac: … 2-{4-[4-(azetidin-1-yl)-7-methylimidazo[4,3-f][1,2,4]triazin-5-yl]-1-methyl-1H-pyrazol-5-yl}-5-(trifluoromethyl …
Matched Description: … of a Modified-Release Formulation of PF-05180999). ... PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability …
Matched Description: … of a Modified-Release Formulation of PF-05180999). ... PF-05180999 is under investigation in clinical trial NCT01530529 (A Study to Assess the Relative Bioavailability …
Emerfetamab
Emerfetamab is a bispecific T cell engager antibody construct with a half-life extension Fc moiety capable of binding to the neonatal Fc receptor.
Investigational
Matched Description: … Emerfetamab is a bispecific T cell engager antibody construct with a half-life extension Fc moiety capable …
Cyclic GMP
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … 3',5'-cyclic GMP ... Guanosine 3',5'-cyclic phosphate ... Guanosine 3',5'-cyclic monophosphate …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. ... Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. ... Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
2,6-Diamino-8-(2-Dimethylaminoethylsulfanylmethyl)-3h-Quinazolin-4-One
Experimental
Matched Name: … 2,6-Diamino-8-(2-Dimethylaminoethylsulfanylmethyl)-3h-Quinazolin-4-One …
Matched Iupac: … 2,6-diamino-8-({[2-(dimethylamino)ethyl]sulfanyl}methyl)-3,4-dihydroquinazolin-4-one …
Matched Iupac: … 2,6-diamino-8-({[2-(dimethylamino)ethyl]sulfanyl}methyl)-3,4-dihydroquinazolin-4-one …
Mepindolol
Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.
Experimental
Matched Iupac: … 1-[(2-methyl-1H-indol-4-yl)oxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. …
Matched Description: … Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. …
Wortmannin
Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Experimental
Matched Iupac: … 10),12(19),14-trien-3-yl acetate ... methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0^{2,10}.0^{5,9}.0^{15,19}]nonadeca-2( …
Matched Description: … This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). ... Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. …
Matched Description: … This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). ... Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. …
8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
Experimental
Matched Name: … 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluoro-9-(pent-4-yn-1-yl)-9H-purin-6-amine …
Matched Iupac: … 8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluoro-9-(pent-4-yn-1-yl)-9H-purin-6-amine …
CDX-6210
CDX-6210 is a modified version of a leucine decarboxylase enzyme from Planctomycetaceae bacterium.
Investigational
Matched Description: … CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_. …
BVX-001
BVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
Investigational
Matched Description: … BVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate. …
Dutogliptin
Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Investigational
Matched Iupac: … [(2R)-1-(2-{[(3R)-pyrrolidin-3-yl]amino}acetyl)pyrrolidin-2-yl]boronic acid …
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Golotimod
SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and INF-g production. Due to this preferential activation of Th1 cytokine production, SCV-07 may show utility in...
Investigational
Matched Iupac: … (2R)-2-amino-4-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}butanoic acid …
Matched Description: … SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like ... T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 …
Matched Description: … SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like ... T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 …
Elsiglutide
Investigational
Vincamine
Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Experimental
Matched Description: … Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Uridine-5'-Diphosphate
A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem]
Experimental
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem] …
Matched Description: … A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [PubChem] …
Cytochrome C
Cytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain.
Investigational
Matched Description: … Cytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain. …
Placental Mesenchymal Stem Cells
The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs). It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells. The placental MSCs (pMSCs) are...
Investigational
Matched Description: … The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs) …
Sumanirole
Investigational
Matched Iupac: … (10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 13151 - 13175 of 13944 in total