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Displaying drugs 1301 - 1325 of 1592 in total
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Matched Products: … Esmolol Hydrochloride In Sodium Chloride …
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Live-well® OsteSAMIN Plus CHONDROITIN Capsule …
Matched Salts name: … Glucosamine sulfate sodium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Live-well OsteSAMIN 1500 Powder ... Live-well™ OSTESAMIN 500 Capsule …
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Synonyms: … Recombinant human granulocyte-macrophage colony stimulating factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon, human
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Medications that increase serum magnesium ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Investigational
Matched Synonyms: … Human elafin …
The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. This factor presents effects related to growth regulation, insulin-like and mitogenic activities. To perform its biological activities, this growth factor can present some dependence to somatotropin. It...
Experimental
Matched Synonyms: … Human oligopeptide-24 ... Human insulin-like growth factor II ... Insulin-like growth factor II (human) …
Matched Description: … and to circulate in the blood. ... This factor presents effects related to growth regulation, insulin-like and mitogenic activities. ... insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene …
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta, recombinant human ... Interferon beta-1a (recombinant human) …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta …
Matched Categories: … Recombinant Human Interferon beta ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Experimental
Matched Name: … 2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid …
Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE).
Investigational
Matched Synonyms: … DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2 …
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Salts name: … Cefalotin sodium
Matched Products: … CEFALOTINA (SODICA)1 G FRASCO AMPOLLA …
Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.
Approved
Matched Synonyms: … Human albumin I-131 ... Human serum albumin I-131 ... Iodinated (131I) human serum albumin …
Matched Description: … radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and
Investigational
Matched Synonyms: … Peptide YY human ... Peptide YY (human) ... Peptide YY human (1-36) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational
Matched Synonyms: … Antithrombin (human variant kw-3357) ... Human antithrombin-iii (atiii, serpin c1) expressed in fucosyl transferase-negative chinese hamster ovary …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and ... It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … BLEOMICINA POLVO LIOFILIZADO PARA INYECCION VIAL POR 15UI …
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Synonyms: … Recombinant human TNF …
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and ... (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Investigational
Matched Synonyms: … Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells) …
Matched Description: … Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, levoleucovorin and leucovorin are both used to counteract the toxic effects of folic …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... sodium levofolinate …
Matched Products: … SODIO LEVOFOLINATO MEDAC …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and
Matched Products: … Paroxetine Hydrochloride Anhydrous
Displaying drugs 1301 - 1325 of 1592 in total